| Gene Symbol | WRN |
| Full Name | Werner Syndrome RecQ Like Helicase |
| Aliases | Page for WRN Protein |
| Protein Type | Enzyme |
| Function | WRN is a multifunctional DNA metabolic enzyme: |
| Subcellular Localization | </th><td>Nucleus, nucleolus</td></tr> |
| Molecular Weight | 164 kDa |
| Ensembl ID | ENSG00000113240 |
| GeneCards | WRN |
| Human Protein Atlas | WRN |
| N-terminal exonuclease domain | 3'→5' exonuclease activity |
| RecQ helicase domain | 3'→5' helicase activity |
| RQC domain | RecQ helicase conserved region |
| HRDC domain | Helicase RNase D C-terminal |
| NLS | Nuclear localization signal |
| Associated Diseases | Aging, Ms, Senescence |
| Interactions | COMPLEMENT, CTC1, LMNA, MDM2, MRE11, MUTYH |
| KG Connections | 26 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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