gene 1,731 words KG: RAB32
Contents

RAB32 Gene

🧬 Gene Info
Gene SymbolRAB32
Full NameRAB32, Member RAS Oncogene Family
Chromosome6q16.3
Functionis an important component in the neurobiology of neurodegenerative diseases.
Molecular Weight25 kDa
Amino Acids225 aa
UniProt ID[Q9NX93](https://www.uniprot.org/uniprot/Q9NX93)
Ensembl IDENSG00000116574
OMIM613735
GeneCardsRAB32
Human Protein AtlasRAB32
GTP-binding domainThe core domain that binds GTP/GDP and mediates switching between active and inactive states
Switch I regionUndergoes conformational changes upon GTP binding, mediating effector interactions
Switch II regionCritical for GTP hydrolysis and effector binding
Hypervariable C-terminal regionContains cysteine residues for geranylgeranylation and membrane anchoring
Associated DiseasesAls, Ms, Parkinson, Parkinson's disease, Tumor
InteractionsLRRK2
KG Connections56 knowledge graph edges
DatabasesGeneCardsNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

RAB32 regulates DRP1
RAB32 associated_with GBM
RAB32 associated_with MMP9
RAB32 associated_with MMP2
RAB32 associated_with DRP1
RAB32 activates LRRK2
GBM associated_with RAB32
DRP1 regulates RAB32
MMP9 associated_with RAB32
MMP2 associated_with RAB32

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