gene 1,061 words KG: SCFD1
Contents

SCFD1

🧬 Gene Info
Gene SymbolSCFD1
Chromosome9q34.3
Functionis a member of the Sec1/Munc18 (SM) protein family that plays essential roles in intracellular vesicle trafficking and membrane fusion events throughout the cell.
Primary Expressionboth excitatory glutamatergic and inhibitory GABAergic neurons - Present in astrocytes and oligodendrocytes - High expression
Molecular Weight41 kDa
Amino Acids372 aa
Exons14
Ensembl IDENSG00000084112
GeneCardsSCFD1
Human Protein AtlasSCFD1
SedlinNamed after the Sedlis syndrome (a form of spondylometaphyseal dysplasia)
Sly1Suppressor of ypt1 in yeast
KIAA0822Formerly used identifier
Associated DiseasesMs
InteractionsAGING, AMPK, EXERCISE, JAK2, KDM5D
KG Connections17 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

SCFD1 interacts_with JAK2
SCFD1 associated_with AKT
SCFD1 interacts_with KDM5D
SCFD1 associated_with FOXO1
SCFD1 upregulates TREM2
OxPC causes SCFD1
SCFD1 modulates SNARE complex formation
AGING interacts_with SCFD1
SCFD1 associated_with APOPTOSIS
SCFD1 interacts_with EXERCISE

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