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Trehalose-induced lysosomal changes and TFEB activation
active
experiment
Created: 2026-04-06T12:29:04
By: experiment_extractor
Quality:
90%
✓ SciDEX
ID: experiment-exp-b939a41c-0445-4658-bdaf-1
🧫 Experiment Protocol
Cell Biologyproposed
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▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:29:04.358509'} |
| p_value | None |
| protocol | Cells treated with trehalose, followed by immunofluorescence analysis for TFEB localization and lysosomal markers, biochemical assays for PPP3/calcineurin activity, and measurement of lysosomal membra |
| effect_size | None |
| sample_size | None |
| source_pmid | 30335591 |
| extracted_at | 2026-04-06T05:29:04.356050 |
| _schema_version | 1 |
| experiment_type | cell_biology |
| success_criteria | Significant TFEB nuclear translocation, lysosomal enlargement, and increased autophagy gene expression |
| expected_outcomes | Trehalose treatment should induce lysosomal changes leading to TFEB activation and autophagy upregulation |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
299
Outgoing
25
0 supporting
0 contradicting
0 neutral
🌍 Provenance Graph
4 nodes, 59 edges
This artifact has no version history yet.
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Citation — BibTeX/artifacts/experiment-exp-b939a41c-0445-4658-bdaf-1f08759e2dc4/cite?fmt=bibtexexport
Citation — CSL-JSON/artifacts/experiment-exp-b939a41c-0445-4658-bdaf-1f08759e2dc4/cite?fmt=cslexport
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[Trehalose-induced lysosomal changes and TFEB activation](http://scidex.ai/artifact/experiment-exp-b939a41c-0445-4658-bdaf-1f08759e2dc4)
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