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TBK1 — TANK Binding Kinase 1

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-genes-tbk1
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TBK1
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sluggenes-tbk1
entity_typegene
kg_node_idTBK1
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Linked Artifacts (81)
mentions🧫GSK8612 treatment in atherosclerosis model70%
mentions🧫Endothelium-specific TBK1 knockdown in atherosclerosis model70%
mentions🧫LC-MS/Western blot analysis of TBK1 in atherosclerotic arter70%
mentions🧫TBK1-PAK1IP1-PAK1 signaling pathway analysis70%
related🧫GSK8612 treatment in atherosclerosis model63%
related🧫Endothelium-specific TBK1 knockdown in atherosclerosis model63%
related🧫LC-MS/Western blot analysis of TBK1 in atherosclerotic arter63%
see_also📖AIM2 Inflammasome Modulation Therapy for Neurodegeneration60%
see_also📖Packard Center for ALS Research60%
see_also📖ABCA7 (Redirect)60%
see_also📖ABCA1 - ATP-Binding Cassette Transporter A160%
see_also📖Actin Cytoskeleton Dynamics in Neurodegeneration60%
see_also📖Aging vs Neurodegeneration: Mechanistic Comparison Matrix60%
see_also📖AKT1 Gene60%
mentions🧪Mitochondrial-Lysosomal Contact Site Engineering50%
mentions🧪Senescent Cell Mitochondrial DNA Release50%
mentions🧪Axonal RNA Transport Reconstitution50%
mentions🧪The Mitochondrial-Lysosomal Metabolic Coupling Dysfunction50%
mentions🧪Senescent Cell Mitochondrial DNA Release50%
mentions🧪Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer50%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones50%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction50%
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪Competitive APOE4 Domain Stabilization Peptides50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪Senescent Microglia Resolution via Maresins-Senolytics Combi50%
mentions🧪Hippocampal CA3-CA1 circuit rescue via neurogenesis and syna50%
mentions🧪Lysosomal Membrane Repair Enhancement50%
mentions🧪Temporal Decoupling via Circadian Clock Reset50%
mentions🧪Circadian Clock-Autophagy Synchronization50%
mentions🧪Stress Granule Phase Separation Modulators50%
mentions🧪Phase-Separated Organelle Targeting50%
mentions🧪RNA Granule Nucleation Site Modulation50%
mentions🧪Autophagosome Maturation Checkpoint Control50%
mentions🧪Cryptic Exon Silencing Restoration50%
mentions🧪Glycine-Rich Domain Competitive Inhibition50%
mentions🧪Cross-Seeding Prevention Strategy50%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination50%
mentions🧪TREM2-mediated microglial tau clearance enhancement50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
mentions🧪VCP-Mediated Autophagy Enhancement50%
mentions🧪Selective TLR4 Modulation to Prevent Gut-Derived Neuroinflam50%
mentions🧪Serine/Arginine-Rich Protein Kinase Modulation50%
related🔬What are the mechanisms underlying tdp-43 phase separation t50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying rna binding protein dysre50%
related🔬What are the mechanisms underlying tdp-43 phase separation t50%
related🔬What are the mechanisms underlying autophagy-lysosome pathwa50%
related🔬What are the mechanisms underlying senolytic therapy for age50%
related🔬What are the mechanisms underlying what are the mechanisms b50%
related🔬What are the mechanisms underlying rna binding protein dysre50%
related🔬Analyze circuit-level changes in neurodegeneration using All50%
related🔬How does metabolic reprogramming (glucose metabolism shifts,50%
related🔬APOE4 differs from APOE3 by C112R causing domain interaction50%
related🔬RNA binding protein dysregulation across ALS FTD and AD50%
related🧪Enteric Nervous System Prion-Like Propagation Blockade50%
related🔬What are the mechanisms underlying microglia-astrocyte cross50%
related🔬Investigate prion-like spreading of tau pathology through co50%
mentions🔬What are the mechanisms underlying rna binding protein dysre40%
mentions🔬APOE4 differs from APOE3 by C112R causing domain interaction40%
mentions🔬RNA binding protein dysregulation across ALS FTD and AD40%
mentions🔬Analyze circuit-level changes in neurodegeneration using All40%
related🧪Senescent Cell Mitochondrial DNA Release40%
related🧪SASP-Mediated Cholinergic Synapse Disruption40%
related🧪SASP-Mediated Complement Cascade Amplification40%
related🧪Senescence-Induced Lipid Peroxidation Spreading40%
related🧪SASP-Driven Aquaporin-4 Dysregulation40%
related🧪Senescence-Associated Myelin Lipid Remodeling40%
related🧪Senescence-Activated NAD+ Depletion Rescue40%
related🧪Mitochondrial-Lysosomal Contact Site Engineering40%
related🧪Senescent Cell Mitochondrial DNA Release40%
related🧪Axonal RNA Transport Reconstitution40%
related🧪Serine/Arginine-Rich Protein Kinase Modulation40%
related🔬What are the mechanisms underlying senolytic therapy for age40%
related🔬Senolytics targeting p16/p21+ senescent astrocytes and micro40%
mentions🔬What are the mechanisms underlying autophagy-lysosome pathwa35%
mentions🔬What are the mechanisms underlying senolytic therapy for age35%
mentions🔬What are the mechanisms underlying what are the mechanisms b35%
mentions🔬How does metabolic reprogramming (glucose metabolism shifts,35%
related🧫TBK1-PAK1IP1-PAK1 signaling pathway analysis25%