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Semorinemab (RG6100)

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slug	therapeutics-semorinemab
entity_type	therapeutic
kg_node_id	None

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wiki-therapeutics-semorinemab → paper-32145678

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cites📄Randomized control trial of evaluation of Clemastine effects80%

mentions🧪LRP1-Dependent Tau Uptake Disruption70%

mentions🧪Microglial Purinergic Reprogramming70%

mentions🧪Circadian-Synchronized LRP1 Pathway Activation70%

mentions🧪Synthetic Biology BBB Endothelial Cell Reprogramming70%

mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides70%

related🧫Macroautophagy Dysfunction in PD - Experiment Design70%

related🧪LRP1-Dependent Tau Uptake Disruption63%

related🧪Microglial Purinergic Reprogramming63%

related🧪Circadian-Synchronized LRP1 Pathway Activation63%

related🧪Synthetic Biology BBB Endothelial Cell Reprogramming63%

related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides63%

see_also📖Extracellular Vesicle and Tunneling Nanotube-Mediated Spread55%

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mentions🧪Purinergic P2Y12 Inverse Agonist Therapy50%

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see_also📖Prion-Like Spread in Neurodegeneration50%

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see_also📖Transdiagnostic Proteomic Changes in Neurodegeneration50%

see_also📖ubiquitin-proteasome-dysfunction-neurodegeneration50%

see_also📖Ubiquitin-Proteasome System Dysfunction in Neurodegeneration50%

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see_also📖vip-vasoactive-intestinal-peptide-signaling-neurodegeneratio50%

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related🔬What are the mechanisms underlying 4r-tau strain-specific sp48%

related🔬Investigate prion-like spreading of tau pathology through co48%

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mentions🧫Anti-Tau Immunotherapy Dosing Optimization44%

mentions🧫Tau PET Pattern as Therapeutic Response Predictor in 4R-Tauo44%

mentions🧫Tau Propagation Causality Test — Does Tau Spread Drive Neuro44%

mentions🧫Microtubule domain analysis in adult axons44%

mentions🧫Tau depletion effects on neuronal development in primary cul44%

mentions🧫Pre-Symptomatic Tau Detection in MAPT Mutation Carriers44%

mentions🔬What are the mechanisms underlying tdp-43 phase separation t40%

mentions🔬What are the mechanisms underlying blood-brain barrier trans40%