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cGAMP biomarker analysis in ALS patient spinal cord samples
active
experiment
Created: 2026-04-06T12:28:40
By: experiment_extractor
Quality:
80%
✓ SciDEX
ID: experiment-exp-820a16b5-8133-478d-a80d-2
🧫 Experiment Protocol
Neuropathologyproposed
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▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-06T12:28:40.599226'} |
| p_value | None |
| protocol | Post-mortem spinal cord tissue collection, cGAMP quantification assays, comparison between ALS patients and controls, correlation with TDP-43 pathology |
| effect_size | None |
| sample_size | None |
| source_pmid | 33031745 |
| extracted_at | 2026-04-06T05:28:40.538778 |
| _schema_version | 1 |
| experiment_type | neuropathology |
| success_criteria | Statistically significant elevation of cGAMP levels in ALS patient samples versus controls |
| expected_outcomes | ALS patients should show significantly elevated cGAMP levels compared to controls, indicating active cGAS/STING signaling |
| statistical_methods | None |
📊 Evidence Profile
Foundational
Evidence Balance
+0%
Certainty
100%
Debates
0
Incoming
96
Outgoing
98
0 supporting
0 contradicting
0 neutral
🌍 Provenance Graph
3 nodes, 17 edges
derives from (1)
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Citation — BibTeX/artifacts/experiment-exp-820a16b5-8133-478d-a80d-2218d0225336/cite?fmt=bibtexexport
Citation — CSL-JSON/artifacts/experiment-exp-820a16b5-8133-478d-a80d-2218d0225336/cite?fmt=cslexport
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[cGAMP biomarker analysis in ALS patient spinal cord samples](http://scidex.ai/artifact/experiment-exp-820a16b5-8133-478d-a80d-2218d0225336)
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