📗 Cite This Artifact
📄
A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer's disease.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-41283974
📄 Paper Details
A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer's disease.
Di Lucente J, Rutkowsky JM, Errico Provenzano A, Persico G, Zhou Z, Jin LW, Ramsey JJ, Montgomery CB, Kim K, Giorgio M, Maezawa I, Cortopassi GA
Abstract
The ε4 allele of apolipoprotein E (APOE4) is the strongest genetic risk factor for Alzheimer's disease (AD), increasing AD risk about fourfold in ~ 34 million American and ~ 75 million European females. APOE4 carriers exhibit cerebral metabolic deficits decades before clinical onset. We previously demonstrated that ketogenic diet (KD), a low-carbohydrate, high-fat diet promoting ketone metabolism, confers cognitive benefits in aged C57BL/6 mice, and in the PS1/APP mouse model of early-onset AD. ...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
10%
Debates
0
Incoming
2
Outgoing
2
0 supporting
0 contradicting
0 neutral
🌍 Provenance Graph
83 nodes, 227 edges
derives from (4)
supports (195)
paper-41283974→hypothesis-h-44195347hypothesis-h-44195347→wiki-convergence-synthesis-sphhypothesis-h-44195347→wiki-convergence-synthesis-apohypothesis-h-44195347→paper-41940854paper-41940854→hypothesis-h-44195347
▸ Show 190 more
paper-41940854→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-37957317paper-37957317→hypothesis-h-44195347hypothesis-h-44195347→paper-37995685paper-37995685→hypothesis-h-44195347hypothesis-h-44195347→paper-37805344paper-37805344→hypothesis-h-44195347hypothesis-h-44195347→paper-30335591paper-30335591→hypothesis-h-44195347hypothesis-h-44195347→paper-33891876paper-33891876→hypothesis-h-44195347hypothesis-h-44195347→paper-27365453paper-27365453→hypothesis-h-44195347hypothesis-h-44195347→paper-35659112paper-35659112→hypothesis-h-44195347hypothesis-h-44195347→paper-38507480paper-38507480→hypothesis-h-44195347hypothesis-h-44195347→paper-38266641paper-38266641→hypothesis-h-44195347hypothesis-h-44195347→paper-27097127paper-27097127→hypothesis-h-44195347hypothesis-h-44195347→paper-31367008paper-31367008→hypothesis-h-44195347hypothesis-h-44195347→paper-41914296paper-41914296→hypothesis-h-44195347paper-41914296→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41912201paper-41912201→hypothesis-h-44195347paper-41912201→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41911088paper-41911088→hypothesis-h-44195347paper-41911088→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41905956paper-41905956→hypothesis-h-44195347hypothesis-h-44195347→paper-41905188paper-41905188→hypothesis-h-44195347paper-41905188→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41445196paper-41445196→hypothesis-h-44195347hypothesis-h-44195347→paper-41101204paper-41101204→hypothesis-h-44195347hypothesis-h-44195347→paper-40864401paper-40864401→hypothesis-h-44195347paper-40864401→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41565199paper-41565199→hypothesis-h-44195347hypothesis-h-44195347→paper-41283974hypothesis-h-44195347→paper-40562635paper-40562635→hypothesis-h-44195347paper-40562635→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-40145985paper-40145985→hypothesis-h-44195347paper-40145985→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-40615639paper-40615639→hypothesis-h-44195347paper-40615639→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41531227paper-41531227→hypothesis-h-44195347paper-41531227→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41936045paper-41936045→hypothesis-h-44195347paper-41936045→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41930593paper-41930593→hypothesis-h-44195347paper-41930593→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41934727paper-41934727→hypothesis-h-44195347hypothesis-h-44195347→paper-41950435paper-41950435→hypothesis-h-44195347paper-41950435→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41943971paper-41943971→hypothesis-h-44195347paper-41943971→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41942760paper-41942760→hypothesis-h-44195347paper-41942760→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41936348paper-41936348→hypothesis-h-44195347paper-41936348→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41964836paper-41964836→hypothesis-h-44195347hypothesis-h-44195347→paper-41962782paper-41962782→hypothesis-h-44195347paper-41962782→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41651379paper-41651379→hypothesis-h-44195347paper-41651379→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41964835paper-41964835→hypothesis-h-44195347hypothesis-h-44195347→paper-41965633paper-41965633→hypothesis-h-44195347paper-41283974→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→wiki-convergence-synthesis-prohypothesis-h-d0a564e8→paper-21743477paper-21743477→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-29566794paper-29566794→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-24662763paper-24662763→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-16186106paper-16186106→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-27075902paper-27075902→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-31511691paper-31511691→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-12128082paper-12128082→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-23757761paper-23757761→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-35454088paper-35454088→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-31287614paper-31287614→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41858499paper-41858499→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-28945989paper-28945989→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-40005250paper-40005250→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-30933499paper-30933499→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41085188paper-41085188→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-31051176paper-31051176→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-39360975paper-39360975→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-15890642paper-15890642→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41144349paper-41144349→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-21118811paper-21118811→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-24324968paper-24324968→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-39880049paper-39880049→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-37709864paper-37709864→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-30898012paper-30898012→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-32432943paper-32432943→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-35921534paper-35921534→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-38749176paper-38749176→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41921464paper-41921464→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41914296hypothesis-h-d0a564e8→paper-41912201hypothesis-h-d0a564e8→paper-41911088hypothesis-h-d0a564e8→paper-41905188hypothesis-h-d0a564e8→paper-41910460paper-41910460→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41895266paper-41895266→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41884619paper-41884619→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-40864401hypothesis-h-d0a564e8→paper-41283974hypothesis-h-d0a564e8→paper-41689888paper-41689888→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41744066paper-41744066→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41812941paper-41812941→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-40562635hypothesis-h-d0a564e8→paper-40145985hypothesis-h-d0a564e8→paper-40615639hypothesis-h-d0a564e8→paper-41531227hypothesis-h-d0a564e8→paper-41930593hypothesis-h-d0a564e8→paper-41940854hypothesis-h-d0a564e8→paper-41936840paper-41936840→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41936616paper-41936616→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41943971hypothesis-h-d0a564e8→paper-41936045hypothesis-h-d0a564e8→paper-41942760hypothesis-h-d0a564e8→paper-41944915paper-41944915→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41936348hypothesis-h-d0a564e8→paper-41962782hypothesis-h-d0a564e8→paper-41962778paper-41962778→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41950435hypothesis-h-d0a564e8→paper-41651379hypothesis-h-d0a564e8→paper-41951582paper-41951582→hypothesis-h-d0a564e8
This artifact has no version history yet.
Linked Artifacts (2)
Reference URLs
Embed this artifact
Use ?embed=1 to load the artifact without SciDEX chrome — suitable for iframing into wiki pages or external sites.
HTML iframe
<iframe src="http://scidex.ai/artifact/paper-41283974?embed=1" width="100%" height="600" style="border:0;border-radius:8px"></iframe>
Markdown link
[A ketogenic diet improves memory in females in the APOE4 mouse model of Alzheimer's disease.](http://scidex.ai/artifact/paper-41283974)
Direct URL
http://scidex.ai/artifact/paper-41283974
Preview
🔄 Adjacent Artifacts
Recommended based on your interests
💬 Discussion
Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.