📗 Cite This Artifact
📄
ApoE-directed CpG nano-immunoadjuvant ameliorates Alzheimer's-like pathology in mice.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-41651379
📄 Paper Details
ApoE-directed CpG nano-immunoadjuvant ameliorates Alzheimer's-like pathology in mice.
Huang X, Sun YY, Qin YR, Chen H, Pan TT et al.
Abstract
Toll-like receptor 9 (TLR9), expressed in both microglia and neurons of the CNS, represents a promising therapeutic target for Alzheimer's disease (AD). While either microglial or neuronal TLR9 activation exerts neuroprotective effects that ameliorate AD pathology and preserve cognitive function, CpG oligodeoxynucleotides (ODNs), the synthetic agonists, cannot cross the blood-brain barrier (BBB). To overcome this, we developed tNCpG, an apolipoprotein E (ApoE)-functionalized polymersome nanocarr...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
10%
Debates
0
Incoming
2
Outgoing
2
0 supporting
0 contradicting
0 neutral
🌍 Provenance Graph
83 nodes, 227 edges
derives from (4)
supports (195)
paper-41651379→hypothesis-h-44195347hypothesis-h-44195347→wiki-convergence-synthesis-sphhypothesis-h-44195347→wiki-convergence-synthesis-apohypothesis-h-44195347→paper-41940854paper-41940854→hypothesis-h-44195347
▸ Show 190 more
paper-41940854→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-37957317paper-37957317→hypothesis-h-44195347hypothesis-h-44195347→paper-37995685paper-37995685→hypothesis-h-44195347hypothesis-h-44195347→paper-37805344paper-37805344→hypothesis-h-44195347hypothesis-h-44195347→paper-30335591paper-30335591→hypothesis-h-44195347hypothesis-h-44195347→paper-33891876paper-33891876→hypothesis-h-44195347hypothesis-h-44195347→paper-27365453paper-27365453→hypothesis-h-44195347hypothesis-h-44195347→paper-35659112paper-35659112→hypothesis-h-44195347hypothesis-h-44195347→paper-38507480paper-38507480→hypothesis-h-44195347hypothesis-h-44195347→paper-38266641paper-38266641→hypothesis-h-44195347hypothesis-h-44195347→paper-27097127paper-27097127→hypothesis-h-44195347hypothesis-h-44195347→paper-31367008paper-31367008→hypothesis-h-44195347hypothesis-h-44195347→paper-41914296paper-41914296→hypothesis-h-44195347paper-41914296→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41912201paper-41912201→hypothesis-h-44195347paper-41912201→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41911088paper-41911088→hypothesis-h-44195347paper-41911088→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41905956paper-41905956→hypothesis-h-44195347hypothesis-h-44195347→paper-41905188paper-41905188→hypothesis-h-44195347paper-41905188→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41445196paper-41445196→hypothesis-h-44195347hypothesis-h-44195347→paper-41101204paper-41101204→hypothesis-h-44195347hypothesis-h-44195347→paper-40864401paper-40864401→hypothesis-h-44195347paper-40864401→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41565199paper-41565199→hypothesis-h-44195347hypothesis-h-44195347→paper-41283974paper-41283974→hypothesis-h-44195347paper-41283974→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-40562635paper-40562635→hypothesis-h-44195347paper-40562635→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-40145985paper-40145985→hypothesis-h-44195347paper-40145985→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-40615639paper-40615639→hypothesis-h-44195347paper-40615639→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41531227paper-41531227→hypothesis-h-44195347paper-41531227→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41936045paper-41936045→hypothesis-h-44195347paper-41936045→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41930593paper-41930593→hypothesis-h-44195347paper-41930593→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41934727paper-41934727→hypothesis-h-44195347hypothesis-h-44195347→paper-41950435paper-41950435→hypothesis-h-44195347paper-41950435→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41943971paper-41943971→hypothesis-h-44195347paper-41943971→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41942760paper-41942760→hypothesis-h-44195347paper-41942760→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41936348paper-41936348→hypothesis-h-44195347paper-41936348→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41964836paper-41964836→hypothesis-h-44195347hypothesis-h-44195347→paper-41962782paper-41962782→hypothesis-h-44195347paper-41962782→hypothesis-h-d0a564e8hypothesis-h-44195347→paper-41651379hypothesis-h-44195347→paper-41964835paper-41964835→hypothesis-h-44195347hypothesis-h-44195347→paper-41965633paper-41965633→hypothesis-h-44195347paper-41651379→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→wiki-convergence-synthesis-prohypothesis-h-d0a564e8→paper-21743477paper-21743477→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-29566794paper-29566794→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-24662763paper-24662763→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-16186106paper-16186106→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-27075902paper-27075902→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-31511691paper-31511691→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-12128082paper-12128082→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-23757761paper-23757761→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-35454088paper-35454088→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-31287614paper-31287614→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41858499paper-41858499→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-28945989paper-28945989→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-40005250paper-40005250→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-30933499paper-30933499→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41085188paper-41085188→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-31051176paper-31051176→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-39360975paper-39360975→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-15890642paper-15890642→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41144349paper-41144349→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-21118811paper-21118811→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-24324968paper-24324968→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-39880049paper-39880049→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-37709864paper-37709864→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-30898012paper-30898012→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-32432943paper-32432943→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-35921534paper-35921534→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-38749176paper-38749176→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41921464paper-41921464→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41914296hypothesis-h-d0a564e8→paper-41912201hypothesis-h-d0a564e8→paper-41911088hypothesis-h-d0a564e8→paper-41905188hypothesis-h-d0a564e8→paper-41910460paper-41910460→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41895266paper-41895266→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41884619paper-41884619→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-40864401hypothesis-h-d0a564e8→paper-41283974hypothesis-h-d0a564e8→paper-41689888paper-41689888→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41744066paper-41744066→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41812941paper-41812941→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-40562635hypothesis-h-d0a564e8→paper-40145985hypothesis-h-d0a564e8→paper-40615639hypothesis-h-d0a564e8→paper-41531227hypothesis-h-d0a564e8→paper-41930593hypothesis-h-d0a564e8→paper-41940854hypothesis-h-d0a564e8→paper-41936840paper-41936840→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41936616paper-41936616→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41943971hypothesis-h-d0a564e8→paper-41936045hypothesis-h-d0a564e8→paper-41942760hypothesis-h-d0a564e8→paper-41944915paper-41944915→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41936348hypothesis-h-d0a564e8→paper-41962782hypothesis-h-d0a564e8→paper-41962778paper-41962778→hypothesis-h-d0a564e8hypothesis-h-d0a564e8→paper-41950435hypothesis-h-d0a564e8→paper-41651379hypothesis-h-d0a564e8→paper-41951582paper-41951582→hypothesis-h-d0a564e8
This artifact has no version history yet.
Linked Artifacts (2)
Reference URLs
Embed this artifact
Use ?embed=1 to load the artifact without SciDEX chrome — suitable for iframing into wiki pages or external sites.
HTML iframe
<iframe src="http://scidex.ai/artifact/paper-41651379?embed=1" width="100%" height="600" style="border:0;border-radius:8px"></iframe>
Markdown link
[ApoE-directed CpG nano-immunoadjuvant ameliorates Alzheimer's-like pathology in mice.](http://scidex.ai/artifact/paper-41651379)
Direct URL
http://scidex.ai/artifact/paper-41651379
Preview
🔄 Adjacent Artifacts
Recommended based on your interests
💬 Discussion
Loading comments...
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.