concept

AKK

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AKK: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

27Connections

0Hypotheses

0Analyses

19Outgoing

8Incoming

0Experiments

No summary available yet. View on Wiki →

💡 Concept Info

Name	AKK
Key Genes/Proteins	CMVS, CD4, HMOX1, OCLN, CDH1, HIF
Related Diseases	Aging, Ms

Pathway Diagram

graph TD
    AKK["AKK"]
    AKK -->|"activates"| Aging["Aging"]
    AKK -->|"activates"| Ms["Ms"]
    AKK -->|"activates"| CD4["CD4"]
    AKK -->|"activates"| HMOX1["HMOX1"]
    AKK -->|"activates"| OCLN["OCLN"]
    AKK -->|"activates"| CDH1["CDH1"]
    CMVS["CMVS"] -->|"activates"| AKK
    CD4 -->|"activates"| AKK
    CDH1 -->|"activates"| AKK
    HIF["HIF"] -->|"activates"| AKK
    HMOX1 -->|"activates"| AKK
    RNA["RNA"] -->|"activates"| AKK
    AND["AND"] -->|"activates"| AKK
    OCLN -->|"activates"| AKK

Outgoing (19)

Target	Relation	Type	Str
Aging	activates	disease	0.65
Ms	activates	disease	0.65
Aging	regulates	disease	0.65
CD4	activates	gene	0.60
HMOX1	activates	gene	0.60
OCLN	activates	gene	0.60
CDH1	activates	gene	0.60
CD4	regulates	gene	0.60
CDH1	regulates	gene	0.60
HMOX1	regulates	gene	0.60
OCLN	regulates	gene	0.60
HIF	activates	gene	0.60
Epithelial	activates	cell_type	0.60
T Cell	activates	cell_type	0.60
RNA	activates	gene	0.60
AND	activates	gene	0.60
Hif-1	activates	protein	0.60
Epithelial Cell	expressed_in	cell_type	0.55
T Cell	expressed_in	cell_type	0.55

Incoming (8)

Source	Relation	Type	Str
CMVS	activates	protein	0.64
CD4	activates	gene	0.60
CDH1	activates	gene	0.60
HIF	activates	gene	0.60
HMOX1	activates	gene	0.60
RNA	activates	gene	0.60
AND	activates	gene	0.60
OCLN	activates	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found