cell_type

Epithelial

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about Epithelial: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

665Connections

0Hypotheses

0Analyses

4Outgoing

50Incoming

No summary available yet. View on Wiki →

🧫 Cell Type Info

Cell Type	Epithelial
Definition	<table class="infobox infobox-cell">
Key Markers	CPT1A, MITOCHONDRIA, SQSTM1, PPARG, RPS6KB1, LRP2, NADH, ATG
Key Pathways	Autophagy, Lipid Metabolism, Mtor, Lysosomal Degradation, Er Stress
Associated Diseases	Ischemia, Cancer, Aging, Als, Fibrosis, Pyroptosis
Linked Hypotheses	59 hypotheses

Wiki Pages (20)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    Epithelial["Epithelial"] -->|"expressed in"| Basal_Ganglia["Basal Ganglia"]
    style Basal_Ganglia fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Epithelial["Epithelial"] -->|"expressed in"| Gray_Matter["Gray Matter"]
    style Gray_Matter fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Epithelial["Epithelial"] -->|"expressed in"| Brainstem["Brainstem"]
    style Brainstem fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    Epithelial["Epithelial"] -->|"expressed in"| Substantia_Nigra["Substantia Nigra"]
    style Substantia_Nigra fill:#1a2a3a,stroke:#4fc3f7,stroke-width:1px,color:#fff
    CPT1A["CPT1A"] -->|"regulates"| Epithelial["Epithelial"]
    style CPT1A fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    MITOCHONDRIA["MITOCHONDRIA"] -->|"activates"| Epithelial["Epithelial"]
    style MITOCHONDRIA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    SQSTM1["SQSTM1"] -->|"regulates"| Epithelial["Epithelial"]
    style SQSTM1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    PPARG["PPARG"] -->|"regulates"| Epithelial["Epithelial"]
    style PPARG fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    RPS6KB1["RPS6KB1"] -->|"regulates"| Epithelial["Epithelial"]
    style RPS6KB1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style Epithelial fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (4)

Target	Relation	Type	Str
Basal Ganglia	expressed_in	brain_region	0.50
Gray Matter	expressed_in	brain_region	0.50
Brainstem	expressed_in	brain_region	0.50
Substantia Nigra	expressed_in	brain_region	0.50

Incoming (661)

Source	Relation	Type	Str
CPT1A	regulates	gene	0.60
MITOCHONDRIA	activates	gene	0.60
SQSTM1	regulates	gene	0.60
PPARG	regulates	gene	0.60
RPS6KB1	regulates	gene	0.60
LRP2	regulates	gene	0.60
NADH	regulates	gene	0.60
ATG	regulates	gene	0.60
PPARA	regulates	gene	0.60
EIF4EBP1	regulates	gene	0.60
MTOR	regulates	gene	0.60
MAP1LC3B	regulates	gene	0.60
RUBCN	regulates	gene	0.60
RAB7A	regulates	gene	0.60
CAT	regulates	gene	0.60
RPS6	regulates	gene	0.60
AUTOPHAGY	regulates	gene	0.60
PIK3C3	regulates	gene	0.60
SREBF1	regulates	gene	0.60
RAS	regulates	gene	0.60
EGFR	regulates	gene	0.60
CTSD	regulates	gene	0.60
MTORC1	regulates	gene	0.60
ACTB	regulates	gene	0.60
LAMP1	regulates	gene	0.60
ATP	regulates	gene	0.60
PPARGC1A	regulates	gene	0.60
CERS2	inhibits	gene	0.60
EMP1	regulates	gene	0.60
TP53	associated_with	gene	0.60
AQP4	expressed_in	gene	0.60
TCR	expressed_in	gene	0.60
APOPTOSIS	inhibits	gene	0.60
RNA	inhibits	gene	0.60
APOPTOSIS	therapeutic_target	gene	0.60
UNC5B	activates	gene	0.60
RNA	regulates	gene	0.60
PRMT1	therapeutic_target	gene	0.60
AUTOPHAGY	therapeutic_target	gene	0.60
PRMT5	therapeutic_target	gene	0.60
DNA	therapeutic_target	gene	0.60
EIF2AK3	interacts_with	gene	0.60
SQSTM1	interacts_with	gene	0.60
HMGB1	interacts_with	gene	0.60
OPTINEURIN	interacts_with	gene	0.60
PPARG	interacts_with	gene	0.60
WNT	regulates	gene	0.60
APC	regulates	gene	0.60
ATF6	regulates	gene	0.60
RPS6KB1	interacts_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Epithelial

Understanding Entity Pages

Wiki Pages (20)

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LIN7B — Lin-7 Homolog B

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IL32