Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about BHB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| SQSTM1 | downregulates | protein | 0.95 |
| Progerin | downregulates | protein | 0.95 |
| glymphatic system | associated_with | pathway | 0.90 |
| AMPK | activates | gene | 0.90 |
| Cellular Senescence | suppresses | process | 0.90 |
| ischemic stroke | treats | disease | 0.85 |
| cerebral edema | associated_with | disease | 0.85 |
| AQP4 | regulates | gene | 0.80 |
| neurological deficits | associated_with | phenotype | 0.80 |
| Hutchinson-Gilford Progeria Syndrome | treats | disease | 0.80 |
| LAMP2A | upregulates | gene | 0.80 |
| HSP70 | upregulates | protein | 0.80 |
| NLRP3 | inhibits | protein | 0.80 |
| Caspase-11 | inhibits | protein | 0.80 |
| Gasdermin | inhibits | protein | 0.80 |
| Alzheimer's disease | treats | disease | 0.80 |
| Alzheimer's Disease | protects_against | disease | 0.75 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ketogenic diet | modulates | drug | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||