concept

BUBR1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about BUBR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

16Connections

0Hypotheses

0Analyses

12Outgoing

4Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	BUBR1
Key Genes/Proteins	AXON, AND, MYELIN, AGING, OLIGODENDROCYTE
Related Diseases	Aging
Related Pathways	Myelination

Wiki Pages (6)

Knowledge base pages for this entity

Pathway Diagram

graph TD
    BUBR1["BUBR1"]
    BUBR1 -->|"regulates"| myelination["myelination"]
    BUBR1 -->|"regulates"| motor_function["motor function"]
    BUBR1 -->|"inhibits"| Oligodendrocyte["Oligodendrocyte"]
    BUBR1 -->|"expressed in"| Progenitor_Cell["Progenitor Cell"]
    OLIGODENDROCYTE["OLIGODENDROCYTE"] -->|"inhibits"| BUBR1

Outgoing (12)

Target	Relation	Type	Str
Aging	associated_with	disease	0.65
myelination	regulates	process	0.60
motor function	regulates	process	0.60
myelin sheath aging	associated_with	process	0.60
Oligodendrocyte	inhibits	cell_type	0.60
AXON	associated_with	gene	0.60
AND	associated_with	gene	0.60
MYELIN	associated_with	gene	0.60
Myelination	associated_with	pathway	0.60
AGING	associated_with	gene	0.60
Progenitor Cell	expressed_in	cell_type	0.55
Oligodendrocyte	expressed_in	cell_type	0.55

Incoming (4)

Source	Relation	Type	Str
AXON	associated_with	gene	0.60
MYELIN	associated_with	gene	0.60
AGING	associated_with	gene	0.60
OLIGODENDROCYTE	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

BUBR1

Understanding Entity Pages

Wiki Pages (6)

KIF18A Gene — Kinesin Family Member 18A

KIF14 Gene

PLK1 Gene

KIF22 — Kinesin Family Member 22