Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about C3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Neuronal Development | inhibits | process | 0.90 |
| Cognitive Impairment | correlates_with | phenotype | 0.90 |
| C3AR | activates | protein | 0.90 |
| C3AR1 | activates | protein | 0.87 |
| Dendritic Arborization | inhibits | process | 0.85 |
| C3AR | interacts_with | protein | 0.72 |
| M2_POLARIZATION | activates | phenotype | 0.64 |
| COGNITIVE_IMPAIRMENT | associated_with | phenotype | 0.64 |
| MICROGLIA | activates | cell_type | 0.64 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| C3aR Blockade Disrupts the Microglial-Astrocyte Feedforward | 0.596 | neuroinflammation | What molecular mechanisms determine whet |
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||