Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CIRCADIAN DISRUPTION: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CIRCADIAN DISRUPTION |
Knowledge base pages for this entity
graph TD
CIRCADIAN_DISRUPTION["CIRCADIAN DISRUPTION"]
CIRCADIAN_DISRUPTION -->|"risk_factor_for"| Metabolic_Health["Metabolic Health"]
CIRCADIAN_DISRUPTION -->|"modulates"| Clock_Gene_Expression["Clock Gene Expression"]
CIRCADIAN_DISRUPTION -->|"promotes"| Gastrointestinal_Disease["Gastrointestinal Disease"]
CIRCADIAN_DISRUPTION -->|"risk_factor_for"| Type_2_Diabetes["Type 2 Diabetes"]
CIRCADIAN_DISRUPTION -->|"risk_factor_for"| Metabolic_Syndrome["Metabolic Syndrome"]
CIRCADIAN_DISRUPTION -->|"contributes to"| Neurodegeneration["Neurodegeneration"]
CIRCADIAN_DISRUPTION -->|"contributes to"| Cognitive_Impairment["Cognitive Impairment"]
CIRCADIAN_DISRUPTION -->|"contributes to"| Obesity["Obesity"]| Target | Relation | Type | Str |
|---|---|---|---|
| OBESITY | associated_with | entity | 0.90 |
| METABOLIC SYNDROME | associated_with | entity | 0.90 |
| TYPE 2 DIABETES | associated_with | entity | 0.90 |
| GASTROINTESTINAL DISEASE | associated_with | entity | 0.85 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Shift Work | causes | phenotype | 0.90 |
| Clock Gene Expression | associated_with | process | 0.85 |
| Social Jet Lag | causes | phenotype | 0.85 |
| Clock Gene Expression | contributes_to | process | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-11 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||