Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DLX5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
DLX5 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, implicated in, activates. Connected to 12 entities in the SciDEX knowledge graph.
| Gene Symbol | DLX5 |
| Full Name | DLX5 |
| Chromosome | 7q22.1 |
| Protein Type | Gene |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Molecular Weight | 32 kDa |
| Amino Acids | 325 aa |
| Exons | 3 |
| NCBI Gene ID | Search NCBI |
| GeneCards | DLX5 |
| Human Protein Atlas | DLX5 |
| Associated Diseases | neurodegeneration |
| Interactions | GENES, AND |
| KG Connections | 13 knowledge graph edges |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
DLX5["<b>DLX5</b>"]
Akt(["Akt"])
DLX5 -->|"therapeutic target"| Akt
Pi3K(["Pi3K"])
DLX5 -->|"therapeutic target"| Pi3K
AKT["AKT"]
DLX5 -->|"therapeutic target"| AKT
CASP3["CASP3"]
DLX5 -->|"therapeutic target"| CASP3
HMGCR["HMGCR"]
DLX5 -->|"therapeutic target"| HMGCR
neurodegeneration["neurodegeneration"]
DLX5 -->|"implicated in"| neurodegeneration
CASP3 -->|"therapeutic target"| DLX5
PI3K["PI3K"]
PI3K -->|"therapeutic target"| DLX5
HMGCR -->|"therapeutic target"| DLX5
GENES["GENES"]
GENES -->|"activates"| DLX5
PTGS2["PTGS2"]
PTGS2 -->|"therapeutic target"| DLX5
AKT -->|"therapeutic target"| DLX5
style DLX5 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||