Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GTPBP4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GTPBP4 |
| Key Genes/Proteins | FMDV VP1, RNA, AUTOPHAGY, Akt, SF3B1, SRSF1 |
| Related Pathways | Autophagy, Mtor, Immune Response |
graph TD
GTPBP4["GTPBP4"]
GTPBP4 -->|"inhibits"| innate_immune_responses["innate immune responses"]
GTPBP4 -->|"promotes"| FMDV_replication["FMDV replication"]
GTPBP4 -->|"activates"| RNA["RNA"]
GTPBP4 -->|"activates"| Autophagy["Autophagy"]
GTPBP4 -->|"activates"| Mtor["Mtor"]
GTPBP4 -->|"activates"| Immune_Response["Immune Response"]
GTPBP4 -->|"activates"| AUTOPHAGY["AUTOPHAGY"]
GTPBP4 -->|"activates"| Akt["Akt"]
FMDV_VP1["FMDV VP1"] -->|"promotes"| GTPBP4
IRF3["IRF3"] -->|"activates"| GTPBP4
AUTOPHAGY -->|"activates"| GTPBP4
AKT["AKT"] -->|"activates"| GTPBP4
RNA -->|"activates"| GTPBP4
AND["AND"] -->|"activates"| GTPBP4
MTOR["MTOR"] -->|"activates"| GTPBP4| Target | Relation | Type | Str |
|---|---|---|---|
| innate immune responses | inhibits | process | 0.90 |
| FMDV replication | promotes | process | 0.90 |
| RNA | activates | gene | 0.60 |
| Autophagy | activates | pathway | 0.60 |
| Mtor | activates | pathway | 0.60 |
| Immune Response | activates | pathway | 0.60 |
| AUTOPHAGY | activates | gene | 0.60 |
| Akt | activates | protein | 0.60 |
| SF3B1 | interacts_with | gene | 0.60 |
| SRSF1 | interacts_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||