SF3B1

Understanding Entity Pages

This page aggregates everything SciDEX knows about SF3B1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

SF3B1 is a gene implicated in neurodegeneration research. Key relationships include: therapeutic target, activates, inhibits. Associated with AD, ALI, ALS. Connected to 118 entities in the SciDEX knowledge graph.

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graph TD
    SF3B1["SF3B1"]
    SF3B1 -->|"target for"| Cancer["Cancer"]
    SF3B1 -->|"target for"| Carcinoma["Carcinoma"]
    SF3B1 -->|"target for"| Ms["Ms"]
    SF3B1 -->|"target for"| Als["Als"]
    SF3B1 -->|"target for"| Cardiovascular["Cardiovascular"]
    SF3B1 -->|"activates"| Inflammation["Inflammation"]
    SF3B1 -->|"target for"| Alzheimer["Alzheimer"]
    SF3B1 -->|"target for"| Heart_Failure["Heart Failure"]
    SF3B1 -->|"target for"| Tumor["Tumor"]
    SF3B1 -->|"inhibits"| ALS["ALS"]
    IDH1["IDH1"] -->|"target for"| SF3B1
    VEGFA["VEGFA"] -->|"target for"| SF3B1
    MDM4["MDM4"] -->|"target for"| SF3B1
    APOB["APOB"] -->|"target for"| SF3B1
    ASXL1["ASXL1"] -->|"activates"| SF3B1
    DNMT3A["DNMT3A"] -->|"activates"| SF3B1
    FAS["FAS"] -->|"target for"| SF3B1
    JUN["JUN"] -->|"inhibits"| SF3B1
    MET["MET"] -->|"inhibits"| SF3B1