entity

HPSE

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about HPSE: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

24Connections

0Hypotheses

0Analyses

18Outgoing

6Incoming

0Experiments

Outgoing (18)

Target	Relation	Type	Str
Glycocalyx	degrades	biomarker	0.95
glomerular endothelial glycocalyx	regulates	process	0.90
kidney function	associated_with	phenotype	0.85
glomerular endothelial glycocalyx	degrades	process	0.85
kidney function	downregulates	phenotype	0.80
ICAM1	activates	gene	0.60
MMP2	activates	gene	0.60
MMP9	activates	gene	0.60
NOS3	activates	gene	0.60
ICAM1	interacts_with	gene	0.60
NOS3	interacts_with	gene	0.60
MMP2	interacts_with	gene	0.60
ICAM1	associated_with	gene	0.60
MMP2	associated_with	gene	0.60
NOS3	associated_with	gene	0.60
endothelial cells	expressed_in	cell_type	0.60
oxidative stress response	participates_in	pathway	0.60
INS	associated_with	gene	0.60

Incoming (6)

Source	Relation	Type	Str
ADAMTS1	activates	gene	0.60
CAV1	activates	gene	0.60
ESM1	activates	gene	0.60
ADAMTS1	interacts_with	gene	0.60
CAV1	interacts_with	gene	0.60
ESM1	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found