Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ESM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| BECN1 | regulates | protein | 0.95 |
| ovarian cancer | associated_with | disease | 0.92 |
| PKM2 | interacts_with | protein | 0.90 |
| Idiopathic Nephrotic Syndrome | downregulates | disease | 0.75 |
| endothelial homeostasis | protects_against | process | 0.70 |
| endothelial cells | expressed_in | cell_type | 0.70 |
| IGF2BP3 | regulates | gene | 0.60 |
| HPSE | activates | gene | 0.60 |
| ICAM1 | activates | gene | 0.60 |
| MMP2 | activates | gene | 0.60 |
| MMP9 | activates | gene | 0.60 |
| NOS3 | activates | gene | 0.60 |
| MMP9 | regulates | gene | 0.60 |
| HPSE | associated_with | gene | 0.60 |
| ICAM1 | associated_with | gene | 0.60 |
| MMP2 | associated_with | gene | 0.60 |
| NOS3 | associated_with | gene | 0.60 |
| autophagy pathway | participates_in | pathway | 0.60 |
| INS | regulates | gene | 0.60 |
| INS | associated_with | gene | 0.60 |
| lipid metabolism | participates_in | pathway | 0.60 |
| benchmark_ot_ad_answer_key:ESM1 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||