Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Inflammatory Mediators: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | INFLAMMATORY |
| Full Name | Inflammatory Mediators |
| GeneCards | INFLAMMATORY |
| Human Protein Atlas | INFLAMMATORY |
| Associated Diseases | Blood-Brain Barrier, DNA, RNA, SIGLEC10 |
| Known Drugs/Compounds | Inflammatory Mediator Receptor Antagonists |
| KG Connections | 9 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
graph TD
Inflammatory_Mediators["Inflammatory Mediators"] -->|"contributes to"| Chronic_Neuroinflammation["Chronic Neuroinflammation"]
style Chronic_Neuroinflammation fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Inflammatory_Mediators["Inflammatory Mediators"] -->|"contributes to"| Neuronal_Death["Neuronal Death"]
style Neuronal_Death fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Inflammatory_Mediators["Inflammatory Mediators"] -->|"contributes to"| Neuronal_Cell_Death["Neuronal Cell Death"]
style Neuronal_Cell_Death fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Inflammatory_Mediators["Inflammatory Mediators"] -->|"contributes to"| Alzheimer_s_Disease["Alzheimer's Disease"]
style Alzheimer_s_Disease fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Inflammatory_Mediators["Inflammatory Mediators"] -->|"mediates"| Pathological_Protein_Aggregati["Pathological Protein Aggregation"]
style Pathological_Protein_Aggregati fill:#1a2a3a,stroke:#ffd54f,stroke-width:1px,color:#fff
Inflammatory_Mediators["Inflammatory Mediators"] -->|"promotes"| depression["depression"]
style depression fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Inflammatory_Mediators["Inflammatory Mediators"] -->|"contributes to"| Radiation_Induced_Intestinal_I["Radiation-Induced Intestinal Injury"]
style Radiation_Induced_Intestinal_I fill:#1a2a3a,stroke:#ef5350,stroke-width:1px,color:#fff
Are["Are"] -->|"regulates"| Inflammatory_Mediators["Inflammatory Mediators"]
style Are fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
Inflammatory_Mediator_Receptor["Inflammatory Mediator Receptor Antagonists"] -.->|"inhibits"| Inflammatory_Mediators["Inflammatory Mediators"]
style Inflammatory_Mediator_Receptor fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
SIGLEC10["SIGLEC10"] -->|"associated"| Inflammatory_Mediators["Inflammatory Mediators"]
style SIGLEC10 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
style Inflammatory_Mediators fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold| Target | Relation | Type | Str |
|---|---|---|---|
| Chronic Neuroinflammation | contributes_to | process | 0.90 |
| Neuronal Death | contributes_to | process | 0.90 |
| Neuronal Cell Death | contributes_to | process | 0.88 |
| Alzheimer's Disease | contributes_to | disease | 0.85 |
| Pathological Protein Aggregation | mediates | phenotype | 0.85 |
| Radiation-Induced Intestinal Injury | contributes_to | disease | 0.85 |
| Alzheimer'S Disease | contributes_to | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Are | regulates | pathway | 0.80 |
| Inflammatory Mediator Receptor Antagonists | inhibits | drug | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-12 | 0 hypotheses
neurodegeneration | 2026-04-02 | 2 hypotheses Top: 0.490
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||