concept

INSC

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about INSC: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections

0Hypotheses

0Analyses

28Outgoing

3Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	INSC
Key Genes/Proteins	CREL, RNA, REL, AND
Related Diseases	Multiple Sclerosis, Senescence

Wiki Pages (5)

Knowledge base pages for this entity

CT1-DAP001 iPS Cell-derived Dopaminergic Progenitors for Parkinson's Disease (NCT06482268)

clinical · 1687 words

→

Pathway Diagram

graph TD
    INSC["INSC"]
    INSC -->|"regulates"| Asymmetric_Stem_Cell_Division["Asymmetric Stem Cell Division"]
    INSC -->|"regulates"| Cell_Fate_Decision["Cell Fate Decision"]
    INSC -->|"involved_in"| Stem_Cell_Differentiation["Stem Cell Differentiation"]
    INSC -->|"involved_in"| Embryonic_Stem_Cell_Differenti["Embryonic Stem Cell Differentiation"]
    INSC -->|"expressed in"| Embryonic_Stem_Cell["Embryonic Stem Cell"]
    INSC -->|"involved_in"| Symmetric_Stem_Cell_Division["Symmetric Stem Cell Division"]
    INSC -->|"involved_in"| Mesendoderm_Development["Mesendoderm Development"]
    REL["REL"] -->|"regulates"| INSC
    CREL["CREL"] -->|"regulates"| INSC
    RNA["RNA"] -->|"inhibits"| INSC

Outgoing (28)

Target	Relation	Type	Str
Asymmetric Stem Cell Division	regulates	process	0.90
Cell Fate Decision	regulates	process	0.90
Stem Cell Differentiation	involved_in	process	0.90
Embryonic Stem Cell Differentiation	involved_in	process	0.90
Embryonic Stem Cell	expressed_in	cell_type	0.85
Asymmetric Stem Cell Division	involved_in	process	0.85
Symmetric Stem Cell Division	involved_in	process	0.85
Mesendoderm Development	involved_in	process	0.80
Multiple Sclerosis	activates	disease	0.65
Senescence	activates	disease	0.65
RNA	inhibits	gene	0.60
REL	regulates	gene	0.60
AND	expressed_in	gene	0.60
Stem Cell	regulates	cell_type	0.60
HMGCR	activates	gene	0.60
Cholesterol	activates	pathway	0.60
Stem Cell	activates	cell_type	0.60
Fibroblast	activates	cell_type	0.60
Neuron	activates	cell_type	0.60
AND	activates	gene	0.60
NEUROTOXICITY	activates	gene	0.60
Neural Progenitor	activates	cell_type	0.60
stem cells	expressed_in	cell_type	0.60
RNA	regulates	gene	0.60
Stem Cell	expressed_in	cell_type	0.55
Progenitor Cell	expressed_in	cell_type	0.55
Fibroblast	expressed_in	cell_type	0.55
Neuron	expressed_in	cell_type	0.55

Incoming (3)

Source	Relation	Type	Str
REL	regulates	gene	0.95
CREL	regulates	gene	0.95
RNA	inhibits	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found