cell_type

stem cells

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about stem cells: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

876Connections

0Hypotheses

0Analyses

8Outgoing

50Incoming

No summary available yet. View on Wiki →

🧫 Cell Type Info

Cell Type	stem cells
Definition	<table class="infobox infobox-cell">
Key Markers	DNA, SQSTM1, RNA, ALS, GBM, MAPK, MTOR, STAT3
Key Pathways	Wnt pathway, autophagy pathway, oxidative stress response, circadian regulation, neurotrophin signaling
Associated Diseases	Neural Tissue Damage, Parkinson'S Disease, Alzheimer'S Disease, Amyotrophic Lateral Sclerosis, Multiple Sclerosis, Stroke
Linked Hypotheses	172 hypotheses

Wiki Pages (21)

Knowledge base pages for this entity

Canonical Page

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

therapeutic · 15567 words

→

Progressive Supranuclear Palsy (PSP)

disease · 12907 words

→

Corticobasal Syndrome (CBS)

disease · 11374 words

→

Pathway Diagram

graph TD
    Wnt_pathway["Wnt pathway"] -->|"regulates"| stem_cells["stem cells"]
    style Wnt_pathway fill:#1a2a3a,stroke:#81c784,stroke-width:1px,color:#fff
    DNA["DNA"] -->|"expressed in"| stem_cells["stem cells"]
    style DNA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    SQSTM1["SQSTM1"] -->|"expressed in"| stem_cells["stem cells"]
    style SQSTM1 fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    RNA["RNA"] -->|"expressed in"| stem_cells["stem cells"]
    style RNA fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    ALS["ALS"] -->|"expressed in"| stem_cells["stem cells"]
    style ALS fill:#1a2a3a,stroke:#ce93d8,stroke-width:1px,color:#fff
    style stem_cells fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0,font-weight:bold

Outgoing (82)

Target	Relation	Type	Str
autophagy pathway	active_in	pathway	0.75
oxidative stress response	active_in	pathway	0.75
circadian regulation	active_in	pathway	0.75
neurotrophin signaling	active_in	pathway	0.65
purinergic signaling	active_in	pathway	0.55
unfolded protein response	active_in	pathway	0.55
Wnt signaling	active_in	pathway	0.55
NAD+ metabolism	active_in	pathway	0.55

Incoming (794)

Source	Relation	Type	Str
Wnt pathway	regulates	pathway	0.90
DNA	expressed_in	gene	0.90
SQSTM1	expressed_in	gene	0.90
RNA	expressed_in	gene	0.90
ALS	expressed_in	gene	0.90
GBM	expressed_in	gene	0.90
MAPK	expressed_in	gene	0.80
MTOR	expressed_in	gene	0.80
STAT3	expressed_in	gene	0.80
TFEB	expressed_in	gene	0.80
LC3	expressed_in	gene	0.80
ROS	expressed_in	gene	0.80
IFN	expressed_in	gene	0.80
EGF	expressed_in	gene	0.80
BECN1	expressed_in	gene	0.80
SOD1	expressed_in	gene	0.80
APOE4	expressed_in	gene	0.80
APOE	expressed_in	gene	0.80
MAP1LC3	expressed_in	gene	0.80
PINK1	expressed_in	gene	0.80
SORL1	expressed_in	gene	0.80
ABCA7	expressed_in	gene	0.80
OLIG2	expressed_in	gene	0.80
EGF	supports	protein	0.80
KGF	supports	protein	0.80
VEGF-Α	supports	protein	0.80
TGF	supports	protein	0.80
MIP	supports	protein	0.80
TDP-43	expressed_in	gene	0.75
NLR	expressed_in	gene	0.70
GABA	expressed_in	gene	0.70
PI3K	expressed_in	gene	0.70
LRRK2	expressed_in	gene	0.70
NRBF2	expressed_in	gene	0.70
GABARAP	expressed_in	gene	0.70
MTORC1	expressed_in	gene	0.70
RHEB	expressed_in	gene	0.70
ERN1	expressed_in	gene	0.70
PIK3C3	expressed_in	gene	0.70
STING	expressed_in	gene	0.70
HSPA8	expressed_in	gene	0.70
AR	expressed_in	gene	0.70
ATG	expressed_in	gene	0.70
MAP1LC3B	expressed_in	gene	0.70
GAPDH	expressed_in	gene	0.70
BCL2	expressed_in	gene	0.70
TARDBP	expressed_in	gene	0.70
LAMP1	expressed_in	gene	0.70
ACTB	expressed_in	gene	0.70
APOE3	expressed_in	gene	0.70

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

stem cells

Understanding Entity Pages

Wiki Pages (21)

adult-neural-stem-cells

cbs-psp-daily-action-plan

Personalized Treatment Plan — Atypical Parkinsonism (CBS/PSP)

AAV Gene Therapy for Neurodevelopmental Epilepsy — Competitive Landscape & Delivery Alternatives

Progressive Supranuclear Palsy (PSP)

Corticobasal Syndrome (CBS)

Parkinson's Disease

Parthanatos in Neurodegeneration

Alpha-Synuclein Pathology

nhp-validation-animal-model

nimodipine-als

Therapeutics

Frontotemporal Dementia (FTD) Mechanistic Pathway

CBS/PSP Treatment Rankings

Multiple System Atrophy

Alzheimer's Disease

Frontotemporal Dementia (FTD)

PD Cure Roadmap

Microglial Cells — Cell Type Hierarchy