Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about NEURAL PROGENITOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | NEURAL PROGENITOR |
graph TD
NEURAL_PROGENITOR["NEURAL PROGENITOR"]
NEURAL_PROGENITOR -->|"expressed in"| Spinal_Cord["Spinal Cord"]
NEURAL_PROGENITOR -->|"expressed in"| Frontal_Lobe["Frontal Lobe"]
NEURAL_PROGENITOR -->|"expressed in"| Cortex["Cortex"]
TREHALOSE["TREHALOSE"] -->|"activates"| NEURAL_PROGENITOR
ATG10["ATG10"] -->|"activates"| NEURAL_PROGENITOR
ATG12["ATG12"] -->|"activates"| NEURAL_PROGENITOR
RNA["RNA"] -->|"interacts"| NEURAL_PROGENITOR
SYP["SYP"] -->|"interacts"| NEURAL_PROGENITOR
ALZHEIMER["ALZHEIMER"] -->|"activates"| NEURAL_PROGENITOR
CSNK2A1["CSNK2A1"] -->|"regulates"| NEURAL_PROGENITOR
TAU["TAU"] -->|"activates"| NEURAL_PROGENITOR| Target | Relation | Type | Str |
|---|---|---|---|
| Cortex | expressed_in | brain_region | 0.50 |
| Frontal Lobe | expressed_in | brain_region | 0.50 |
| Spinal Cord | expressed_in | brain_region | 0.50 |
| Source | Relation | Type | Str |
|---|---|---|---|
| SYP | interacts_with | gene | 0.60 |
| GABA | regulates | gene | 0.60 |
| INSC | activates | gene | 0.60 |
| PRESENILIN | associated_with | gene | 0.60 |
| ALZHEIMER | associated_with | gene | 0.60 |
| AMYLOID | associated_with | gene | 0.60 |
| MYELIN | contributes_to | gene | 0.60 |
| PPARGC1A | associated_with | gene | 0.60 |
| TFEB | associated_with | gene | 0.60 |
| LAMP1 | associated_with | gene | 0.60 |
| CTSB | associated_with | gene | 0.60 |
| BAG3 | associated_with | gene | 0.60 |
| HSPA8 | associated_with | gene | 0.60 |
| TREH | associated_with | gene | 0.60 |
| SOD1 | associated_with | gene | 0.60 |
| ATG10 | activates | gene | 0.60 |
| ATG12 | activates | gene | 0.60 |
| PLP1 | inhibits | gene | 0.60 |
| GFAP | inhibits | gene | 0.60 |
| MBP | inhibits | gene | 0.60 |
| MAG | inhibits | gene | 0.60 |
| OLIG1 | inhibits | gene | 0.60 |
| TREHALOSE | activates | gene | 0.60 |
| ALS | associated_with | gene | 0.60 |
| HUNTINGTON | associated_with | gene | 0.60 |
| DNA | associated_with | gene | 0.60 |
| STROKE | regulates | gene | 0.60 |
| MITOCHONDRIA | regulates | gene | 0.60 |
| NAD | regulates | gene | 0.60 |
| PARKINSON | regulates | gene | 0.60 |
| AXON | associated_with | gene | 0.60 |
| ATP | regulates | gene | 0.60 |
| LAMP2A | associated_with | gene | 0.60 |
| AMYLOID-BETA | activates | gene | 0.60 |
| STROKE | expressed_in | gene | 0.60 |
| AMYLOID | activates | gene | 0.60 |
| AGING | activates | gene | 0.60 |
| PARKINSON | associated_with | gene | 0.60 |
| AUTOPHAGY | associated_with | gene | 0.60 |
| RNA | associated_with | gene | 0.60 |
| ATG | associated_with | gene | 0.60 |
| ALZHEIMER | regulates | gene | 0.60 |
| HMGCR | activates | gene | 0.60 |
| CCL3 | associated_with | gene | 0.60 |
| CX3CR1 | associated_with | gene | 0.60 |
| TNF | associated_with | gene | 0.60 |
| APP | associated_with | gene | 0.60 |
| TLR2 | associated_with | gene | 0.60 |
| CCL5 | associated_with | gene | 0.60 |
| RNA | interacts_with | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning NEURAL PROGENITOR in their description or question text
No additional research found