Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KIF23: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | KIF23 |
| Full Name | Kinesin Family Member 23 (Mitotic Kinesin-Like Protein 1) |
| Chromosome | 15q23 |
| Protein Type | Kinesin motor protein, MKLP1 subfamily |
| Function | KIF23 (also known as MKLP1 - Mitotic Kinesin-Like Protein 1) is a plus-end directed kinesin motor protein that plays essential roles in cell division and intracellular transport. |
| Primary Expression | Ubiquitous, high in mitotic cells |
| UniProt ID | Q9Y207 |
| NCBI Gene ID | 9493 |
| Ensembl ID | ENSG00000167525 |
| OMIM | 605647 |
| GeneCards | KIF23 |
| Human Protein Atlas | KIF23 |
| Protein Class | Kinesin motor protein, MKLP1 subfamily |
| Associated Diseases | neurodegeneration |
| KG Connections | 14 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KIF23["<b>KIF23</b>"]
Cancer{"Cancer"}
KIF23 -->|"expressed in"| Cancer
Tumor{"Tumor"}
KIF23 -->|"expressed in"| Tumor
KIF11["KIF11"]
KIF23 -->|"associated with"| KIF11
COL1A1["COL1A1"]
KIF23 -->|"associated with"| COL1A1
DNM1L["DNM1L"]
KIF23 -->|"associated with"| DNM1L
neurodegeneration["neurodegeneration"]
KIF23 -->|"implicated in"| neurodegeneration
PSMA3["PSMA3"]
PSMA3 -->|"associated with"| KIF23
CANCER["CANCER"]
CANCER -->|"expressed in"| KIF23
style KIF23 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| Cancer | expressed_in | disease | 0.65 |
| Tumor | expressed_in | disease | 0.65 |
| KIF11 | associated_with | gene | 0.60 |
| DNM1L | associated_with | gene | 0.60 |
| Kinesin | associated_with | protein | 0.60 |
| COL1A1 | associated_with | gene | 0.60 |
| Apoptosis | causes | pathway | 0.60 |
| Cell Cycle | causes | pathway | 0.60 |
| Neurogenesis | causes | pathway | 0.60 |
| Neuron | causes | cell_type | 0.60 |
| Cytokine | causes | protein | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||