DNM1L

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNM1L: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

DNM1L is a gene implicated in neurodegeneration research. Key relationships include: interacts with, associated with, activates. Associated with AD, ALI, ALS. Connected to 466 entities in the SciDEX knowledge graph.

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graph TD
    DNM1L["DNM1L"] -->|"Interacts With"| Dementia["Dementia"]
    DNM1L["DNM1L"] -->|"Interacts With"| Cardiovascular["Cardiovascular"]
    DNM1L["DNM1L"] -->|"Interacts With"| Als["Als"]
    DNM1L["DNM1L"] -->|"Interacts With"| Alzheimer["Alzheimer"]
    DNM1L["DNM1L"] -->|"Interacts With"| Parkinson["Parkinson"]
    DNM1L["DNM1L"] -->|"Interacts With"| Ms["Ms"]
    DNM1L["DNM1L"] -->|"Activates"| Cancer["Cancer"]
    DNM1L["DNM1L"] -->|"Activates"| Inflammation["Inflammation"]
    CKLF["CKLF"] -->|"Increases Risk"| DNM1L["DNM1L"]
    CKLF1["CKLF1"] -->|"Increases Risk"| DNM1L["DNM1L"]
    ROS["ROS"] -->|"Activates"| DNM1L["DNM1L"]
    CAT["CAT"] -->|"Interacts With"| DNM1L["DNM1L"]
    OPTN["OPTN"] -->|"Interacts With"| DNM1L["DNM1L"]
    style DNM1L fill:#8d4900,color:#e0e0e0
    style Dementia fill:#b71c1c,color:#e0e0e0
    style Cardiovascular fill:#b71c1c,color:#e0e0e0
    style Als fill:#b71c1c,color:#e0e0e0
    style Alzheimer fill:#b71c1c,color:#e0e0e0
    style Parkinson fill:#b71c1c,color:#e0e0e0
    style Ms fill:#b71c1c,color:#e0e0e0
    style Cancer fill:#b71c1c,color:#e0e0e0
    style Inflammation fill:#b71c1c,color:#e0e0e0
    style CKLF fill:#0d47a1,color:#e0e0e0
    style CKLF1 fill:#8d4900,color:#e0e0e0
    style ROS fill:#607D8B,color:#e0e0e0
    style CAT fill:#8d4900,color:#e0e0e0
    style OPTN fill:#8d4900,color:#e0e0e0