concept

LOC100911717

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LOC100911717: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

31Connections

0Hypotheses

0Analyses

23Outgoing

8Incoming

No summary available yet. View on Wiki →

💡 Concept Info

Name	LOC100911717
Key Genes/Proteins	GAP43
Related Diseases	Myocardial Infarction, Ventricular Arrhythmia, ventricular arrhythmias, Cardiovascular, Inflammation

Wiki Pages (1)

Knowledge base pages for this entity

GAP43 Gene

gene · 522 words

→

Pathway Diagram

graph TD
    LOC100911717["LOC100911717"]
    LOC100911717 -->|"regulates"| Sympathetic_Remodeling["Sympathetic Remodeling"]
    LOC100911717 -->|"upregulates"| M1_type_Macrophage["M1-type Macrophage"]
    LOC100911717 -->|"targets"| GAP43["GAP43"]
    LOC100911717 -.biomarker for.-> Myocardial_Infarction["Myocardial Infarction"]
    LOC100911717 -->|"activates"| Cardiovascular["Cardiovascular"]
    LOC100911717 -->|"activates"| Inflammation["Inflammation"]
    LOC100911717 -->|"activates"| LNCRNA["LNCRNA"]
    INFLAMMATION["INFLAMMATION"] -->|"activates"| LOC100911717
    GAP43 -->|"activates"| LOC100911717
    RNA["RNA"] -->|"activates"| LOC100911717
    AND["AND"] -->|"activates"| LOC100911717
    LNCRNA -->|"activates"| LOC100911717

Outgoing (23)

Target	Relation	Type	Str
GAP43	interacts_with	gene	0.95
Sympathetic Remodeling	regulates	process	0.90
M1-type Macrophage	upregulates	cell_type	0.90
M1 Macrophage	expressed_in	cell_type	0.90
M1-type macrophages	expressed_in	cell_type	0.90
GAP43	targets	gene	0.85
Myocardial Infarction	upregulates	disease	0.85
GAP43	downregulates	gene	0.85
Ventricular Arrhythmia	promotes	phenotype	0.85
Myocardial Infarction	involved_in	disease	0.85
sympathetic remodeling	mediates	process	0.85
ventricular arrhythmias	contributes_to	phenotype	0.80
Myocardial Infarction	biomarker_for	disease	0.75
Cardiovascular	activates	disease	0.65
Inflammation	activates	disease	0.65
LNCRNA	activates	gene	0.60
GAP43	activates	gene	0.60
RNA	activates	gene	0.60
Macrophage	activates	cell_type	0.60
AND	activates	gene	0.60
macrophages	expressed_in	cell_type	0.60
RNA	interacts_with	gene	0.60
Macrophage	expressed_in	cell_type	0.55

Incoming (8)

Source	Relation	Type	Str
INFLAMMATION	activates	gene	0.60
GAP43	activates	gene	0.60
RNA	activates	gene	0.60
AND	activates	gene	0.60
LNCRNA	activates	gene	0.60
GAP43	regulates	gene	0.60
GAP43	interacts_with	gene	0.60
GAP43	associated_with	gene	0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found