GAP43

Understanding Entity Pages

This page aggregates everything SciDEX knows about GAP43: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

Growth Associated Protein 43 (Neuromodulin) protein in neurodegeneration

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graph TD
    GAP43["<b>GAP43</b>"]
    Cardiovascular{"Cardiovascular"}
    GAP43 -->|"activates"| Cardiovascular
    Cardiac{"Cardiac"}
    GAP43 -->|"activates"| Cardiac
    Inflammation{"Inflammation"}
    GAP43 -->|"activates"| Inflammation
    Aging{"Aging"}
    GAP43 -->|"interacts with"| Aging
    Als{"Als"}
    GAP43 -->|"activates"| Als
    Ms{"Ms"}
    GAP43 -->|"activates"| Ms
    GAP43 -->|"regulates"| Cardiovascular
    GAP43 -->|"regulates"| Inflammation
    GAP43 -->|"inhibits"| Aging
    Cancer{"Cancer"}
    GAP43 -->|"activates"| Cancer
    Tumor{"Tumor"}
    GAP43 -->|"activates"| Tumor
    Glioblastoma{"Glioblastoma"}
    GAP43 -->|"activates"| Glioblastoma
    h_6ce4884a["h-6ce4884a"]
    h_6ce4884a -->|"therapeutic target"| GAP43
    h_6ce4884a -->|"targets"| GAP43
    GFAP["GFAP"]
    GFAP -->|"inhibits"| GAP43
    MBP["MBP"]
    MBP -->|"inhibits"| GAP43
    GENES["GENES"]
    GENES -->|"inhibits"| GAP43
    MANF["MANF"]
    MANF -->|"inhibits"| GAP43
    ACHE["ACHE"]
    ACHE -->|"activates"| GAP43
    ERK["ERK"]
    ERK -->|"associated with"| GAP43
    ELAVL3["ELAVL3"]
    ELAVL3 -->|"inhibits"| GAP43
    INFLAMMATION["INFLAMMATION"]
    INFLAMMATION -->|"activates"| GAP43
    ERK -->|"transports"| GAP43
    ROS["ROS"]
    ROS -->|"activates"| GAP43
    style GAP43 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0