Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about Metabolic Dysfunction: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Alzheimer's Disease Progression | contributes_to | phenotype | 0.90 |
| age-related diseases | associated_with | disease | 0.80 |
| Alzheimer'S Disease | risk_factor_for | disease | 0.80 |
| Alzheimer's disease | causes | disease | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Tumour Extracellular Vesicles | associated_with | process | 0.92 |
| Metabolic Dysfunction-Associated Steatotic Liver Disease | associated_with | disease | 0.90 |
| Extracellular Vesicles | mediates | process | 0.88 |
| NAD+ Biosynthesis | contributes_to | pathway | 0.85 |
| Aqp1 Blockade | associated_with | mechanism | 0.85 |
| α-lipoic acid | protects_against | compound | 0.85 |
| Gut Microbiota | modulates | cell_type | 0.85 |
| plasma proteins | involved_in | protein | 0.80 |
| AQP1 | modulates | gene | 0.75 |
| MTOR | activates | protein | 0.70 |
| mTOR | activates | protein | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-13 | 0 hypotheses
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||