protein

NF1PROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about NF1PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Analyses

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0Debates

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🔬 Protein Info

Gene Symbol	NF1PROTEIN
Full Name	Neurofibromin 1
Chromosome	17q11.2
Protein Family	Ras GTPase-activating protein (Ras-GAP) family
Primary Expression	High in brain, spinal cord, peripheral nerves
Molecular Weight	327 kDa (2,818 amino acids)
Amino Acids	2,818 amino acids
UniProt ID	P21359
GeneCards	NF1PROTEIN
Human Protein Atlas	NF1PROTEIN
Associated Diseases	Als, Cancer, epilepsy, frontotemporal dementia
Interactions	AKT, AKT3, AND, BRAF, CANCER, CDK4
KG Connections	253 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: NF1PROTEIN — AlphaFold P21359 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

nf1-protein

protein · 4422 words

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Pathway Diagram

graph TD
    NF1PROTEIN["NF1PROTEIN"]
    neurodegeneration["neurodegeneration"]
    NF1PROTEIN -->|"implicated_in"| neurodegeneration
    style NF1PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning NF1PROTEIN in their description or question text

No additional research found