NME8

protein-coding External Resolution
GeneCards NCBI PubMed

External Info (via mygene)

SymbolNME8
NameNME/NM23 family member 8
Typeprotein-coding
Sourcemygene

Summary

This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009].

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