gene

SNCB

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SNCB: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections
0Hypotheses
0Analyses
16Outgoing
12Incoming

Summary

Page for SNCB Gene

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🧬 Gene Info
Gene SymbolSNCB
Full NameBeta-Synuclein
Chromosome5q35.2
FunctionBeta-synuclein is expressed at high levels in the brain, particularly in presynaptic terminals where it performs several important functions:
Molecular Weight14 kDa
Amino Acids134 aa
UniProt IDP37840
NCBI Gene ID6622
Ensembl IDENSG00000100030
OMIM163890
GeneCardsSNCB
Human Protein AtlasSNCB
Protein Length134 amino acids
Associated Diseasesneurodegeneration
KG Connections28 knowledge graph edges
DatabasesGeneCardsHPASTRING
🔮 Predicted Structure: SNCB — AlphaFold P37840 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (17)

Knowledge base pages for this entity

Canonical Page

SNCB Gene

gene · 1573 words

Beta-Synuclein Protein

protein · 3143 words

Gamma-Synuclein Protein

protein · 3069 words

Beta-Synuclein Protein

protein · 2541 words

SNCAG — Synuclein Gamma

gene · 1895 words

STMN1 — Stathmin 1

gene · 1889 words

Pathway Diagram

graph TD
    SNCB["<b>SNCB</b>"]
    Traumatic_Brain_Injury{"Traumatic Brain Injury"}
    SNCB -->|"expressed_in"| Traumatic_Brain_Injury
    SNCG(["SNCG"])
    SNCB -->|"expressed_in"| SNCG
    STMN1(["STMN1"])
    SNCB -->|"expressed_in"| STMN1
    GAP43(["GAP43"])
    SNCB -->|"expressed_in"| GAP43
    HSPE1(["HSPE1"])
    SNCB -->|"expressed_in"| HSPE1
    BRAIN_INJURY(["BRAIN INJURY"])
    SNCB -->|"expressed_in"| BRAIN_INJURY
    NDUFS6(["NDUFS6"])
    NDUFS6 -->|"expressed_in"| SNCB
    LDHB(["LDHB"])
    LDHB -->|"expressed_in"| SNCB
    MAPT(["MAPT"])
    MAPT -->|"expressed_in"| SNCB
    GENES(["GENES"])
    GENES -->|"expressed_in"| SNCB
    style SNCB fill:#1a3a4a,stroke:#ce93d8,stroke-width:3px,color:#ce93d8

Outgoing (16)

TargetRelationTypeStr
Traumatic Brain Injuryexpressed_indisease0.65
SNCGexpressed_ingene0.60
STMN1expressed_ingene0.60
GAP43expressed_ingene0.60
HSPE1expressed_ingene0.60

Incoming (12)

SourceRelationTypeStr
NDUFS6expressed_ingene0.60
MAPTexpressed_ingene0.60
GAP43expressed_ingene0.60
HSPE1expressed_ingene0.60
STMN1expressed_ingene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found