Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about SNCG: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Comprehensive page for Gamma-Synuclein (SNCG) in Neurodegeneration and Cancer
| Gene Symbol | SNCG |
| Full Name | Gamma-Synuclein |
| Chromosome | 10q23.2-q23.3 |
| Protein Family | Synuclein (alpha, beta, gamma) |
| Function | encodes gamma-synuclein (also known as synoretin or BCSG1), the third member of the synuclein family of proteins |
| Primary Expression | the nervous system and has been implicated in various neurodegenerative processes |
| Molecular Weight | 13.0 kDa |
| Amino Acids | 127 aa |
| UniProt ID | P37841 |
| NCBI Gene ID | 6623 |
| Ensembl ID | ENSG00000173267 |
| OMIM | 162267 |
| GeneCards | SNCG |
| Human Protein Atlas | SNCG |
| Alpha-synuclein (SNCA) | The most studied member, central to Parkinson's disease pathogenesis |
| Associated Diseases | neurodegeneration |
| KG Connections | 24 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
SNCG["<b>SNCG</b>"]
Traumatic_Brain_Injury{"Traumatic Brain Injury"}
SNCG -->|"expressed_in"| Traumatic_Brain_Injury
STMN1(["STMN1"])
SNCG -->|"expressed_in"| STMN1
GAP43(["GAP43"])
SNCG -->|"expressed_in"| GAP43
HSPE1(["HSPE1"])
SNCG -->|"expressed_in"| HSPE1
BRAIN_INJURY(["BRAIN INJURY"])
SNCG -->|"expressed_in"| BRAIN_INJURY
MAPT(["MAPT"])
SNCG -->|"expressed_in"| MAPT
NDUFS6(["NDUFS6"])
NDUFS6 -->|"expressed_in"| SNCG
LDHB(["LDHB"])
LDHB -->|"expressed_in"| SNCG
SNCB(["SNCB"])
SNCB -->|"expressed_in"| SNCG
style SNCG fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#4fc3f7| Target | Relation | Type | Str |
|---|---|---|---|
| Traumatic Brain Injury | expressed_in | disease | 0.65 |
| STMN1 | expressed_in | gene | 0.60 |
| GAP43 | expressed_in | gene | 0.60 |
| HSPE1 | expressed_in | gene | 0.60 |
| MAPT | expressed_in | gene | 0.60 |
| NDUFS6 | expressed_in | gene | 0.60 |
| BRAIN INJURY | expressed_in | gene | 0.60 |
| AND | expressed_in | gene | 0.60 |
| LDHB | expressed_in | gene | 0.60 |
| Temporal Lobe | expressed_in | brain_region | 0.55 |
| Frontal Lobe | expressed_in | brain_region | 0.55 |
| Cortex | expressed_in | brain_region | 0.55 |
| STMN1 | co_expressed_with | gene | 0.50 |
| Proteins | expressed_in | protein | 0.50 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||