protein

SYNPOPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about SYNPOPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Experiments

Summary

Synaptopodin (Synpo Protein) is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.

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🔬 Protein Info

Gene Symbol	SYNPO
Full Name	synpo-protein
Chromosome	5q33.1
Protein Type	Protein
Function	encodes a unique actin-associated protein that plays essential roles in both the kidney and the brain.
Subcellular Localization	** Dendritic spines, spine apparatus
Molecular Weight	100 kDa
Amino Acids	007 aa
Exons	24
Pathways	epigenetic regulation, neurotrophin signaling
UniProt ID	Q9Y7X6
NCBI Gene ID	11345
Ensembl ID	ENSG00000172459
OMIM	608005
GeneCards	SYNPO
Human Protein Atlas	SYNPO
Associated Diseases	ALS, Alzheimer, dementia, frontotemporal, neurodegeneration
Interactions	XRCC1, Actin, BDNF, CAMK2A, NGF, PARP1
KG Connections	41 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: SYNPOPROTEIN — AlphaFold SEARCH Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

synpo-protein

protein · 595 words

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Pathway Diagram

graph TD
    SYNPOPROTEIN["SYNPOPROTEIN"]
    neurodegeneration["neurodegeneration"]
    SYNPOPROTEIN -->|"implicated_in"| neurodegeneration
    style SYNPOPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found