concept

TMEM16A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about TMEM16A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

28Connections
0Hypotheses
0Analyses
21Outgoing
7Incoming

No summary available yet. View on Wiki →

💡 Concept Info
NameTMEM16A
Key Genes/ProteinsSTROKE, PIEZO1, TRPA1
Related DiseasesAlzheimer, Cardiovascular, Hypertension, Stroke
Related Pathwayscontractility

Wiki Pages (6)

Knowledge base pages for this entity

ANO9 — Anoctamin 9

gene · 2171 words

ANO8 (Anoctamin 8)

gene · 1902 words

ano6

gene · 932 words

ANO7 (Anoctamin 7 (TMEM16G))

gene · 728 words

ANO1 (Anoctamin 1 (TMEM16A))

gene · 641 words

Pathway Diagram

graph TD
    TMEM16A["TMEM16A"]
    TMEM16A -->|"regulates"| Alzheimer["Alzheimer"]
    TMEM16A -->|"regulates"| Cardiovascular["Cardiovascular"]
    TMEM16A -->|"regulates"| Hypertension["Hypertension"]
    TMEM16A -->|"regulates"| Stroke["Stroke"]
    TMEM16A -->|"regulates"| STROKE["STROKE"]
    TMEM16A -->|"regulates"| PIEZO1["PIEZO1"]
    TMEM16A -->|"regulates"| Endothelial["Endothelial"]
    TMEM16A -->|"regulates"| Neuron["Neuron"]
    TRPV4["TRPV4"] -->|"regulates"| TMEM16A
    ALZHEIMER["ALZHEIMER"] -->|"regulates"| TMEM16A
    TRPA1["TRPA1"] -->|"regulates"| TMEM16A
    AND["AND"] -->|"regulates"| TMEM16A
    ALZHEIMER_S_DISEASE["ALZHEIMER'S DISEASE"] -->|"regulates"| TMEM16A
    STROKE -->|"regulates"| TMEM16A
    PIEZO1 -->|"regulates"| TMEM16A

Outgoing (21)

TargetRelationTypeStr
Pericytesexpressed_incell_type0.85
Pericyte Contractilityassociated_withprocess0.80
Blood Flow Regulationassociated_withprocess0.80
Blood Flow Responseassociated_withprocess0.80
blood flow responsesassociated_withprocess0.80

Incoming (7)

SourceRelationTypeStr
TRPV4regulatesgene0.60
ALZHEIMERregulatesgene0.60
TRPA1regulatesgene0.60
ANDregulatesgene0.60
ALZHEIMER'S DISEASEregulatesgene0.60

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found