Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about DIABETIC NEPHROPATHY: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | DIABETIC NEPHROPATHY |
Knowledge base pages for this entity
graph TD
DIABETIC_NEPHROPATHY["DIABETIC NEPHROPATHY"]
Diabetes_Mellitus["Diabetes Mellitus"] -->|"causes"| DIABETIC_NEPHROPATHY
PI3K_AKT_GSK3_["PI3K/AKT/GSK3beta"] -->|"target for"| DIABETIC_NEPHROPATHY
STAT3["STAT3"] -->|"target for"| DIABETIC_NEPHROPATHY
Quercetin["Quercetin"] -.protects against.-> DIABETIC_NEPHROPATHY
Autophagy["Autophagy"] -->|"involved_in"| DIABETIC_NEPHROPATHY
SIRT1["SIRT1"] -->|"target for"| DIABETIC_NEPHROPATHY
Ferroptosis["Ferroptosis"] -->|"involved_in"| DIABETIC_NEPHROPATHY
phillygenin["phillygenin"] -->|"treats"| DIABETIC_NEPHROPATHY| Target | Relation | Type | Str |
|---|---|---|---|
| Ferroptosis | associated_with | process | 0.90 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Diabetes Mellitus | causes | disease | 0.95 |
| PI3K/AKT/GSK3β | therapeutic_target | pathway | 0.95 |
| STAT3 | therapeutic_target | protein | 0.95 |
| Quercetin | protects_against | compound | 0.95 |
| SIRT1 | therapeutic_target | gene | 0.90 |
| Autophagy | involved_in | process | 0.90 |
| Ferroptosis | involved_in | process | 0.90 |
| Ferroptosis | associated_with | process | 0.90 |
| phillygenin | treats | drug | 0.88 |
| Type 2 Diabetes Mellitus | causes | disease | 0.88 |
| Vitamin D | protects_against | compound | 0.85 |
| Autophagy Disorder | contributes_to | phenotype | 0.85 |
| isoquercitrin | treats | drug | 0.85 |
| Metformin | treats | drug | 0.85 |
| Ferroptosis | causes | process | 0.85 |
| Ferroptosis | contributes_to | process | 0.85 |
| Baicalin | associated_with | chemical | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||