concept

DIABETES MELLITUS

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DIABETES MELLITUS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

1215Connections
0Hypotheses
0Analyses
50Outgoing
50Incoming

Summary

DIABETES MELLITUS is a concept in neurodegeneration research. Key relationships include: activates, therapeutic target, associated with. Associated with ALS, Aging, Als. Connected to 770 entities in the SciDEX knowledge graph.

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💡 Concept Info
NameDIABETES MELLITUS
Key Genes/ProteinsDIABETIC RETINOPATHY
Related DiseasesDiabetes, Als, Cancer, Aging, Inflammation
Related PathwaysOxidative Stress

Wiki Pages (20)

Knowledge base pages for this entity

cbs-psp-daily-action-plan

therapeutic · 30834 words

Parkinson's Disease

disease · 8807 words

Alzheimer's Disease

disease · 5265 words

williams-syndrome

disease · 5022 words

Vascular Cognitive Impairment (VCI)

disease · 4530 words

Pathway Diagram

graph TD
    DIABETES_MELLITUS["DIABETES MELLITUS"]
    DIABETES_MELLITUS -->|"causes"| DIABETIC_RETINOPATHY["DIABETIC RETINOPATHY"]
    DIABETES_MELLITUS -->|"target for"| Fibrosis["Fibrosis"]
    DIABETES_MELLITUS -->|"activates"| Cardiovascular["Cardiovascular"]
    DIABETES_MELLITUS -->|"activates"| Neuropathy["Neuropathy"]
    DIABETES_MELLITUS -->|"activates"| Als["Als"]
    DIABETES_MELLITUS -->|"activates"| Cancer["Cancer"]
    DIABETES_MELLITUS -->|"target for"| Ms["Ms"]
    MTOR["MTOR"] -->|"target for"| DIABETES_MELLITUS
    MTORC1["MTORC1"] -->|"target for"| DIABETES_MELLITUS
    TXNIP["TXNIP"] -->|"target for"| DIABETES_MELLITUS
    NOX4["NOX4"] -->|"activates"| DIABETES_MELLITUS
    PI3K["PI3K"] -->|"activates"| DIABETES_MELLITUS
    AKT["AKT"] -->|"activates"| DIABETES_MELLITUS
    NF__B["NF-KappaB"] -->|"activates"| DIABETES_MELLITUS
    OXIDATIVE_STRESS["OXIDATIVE STRESS"] -->|"target for"| DIABETES_MELLITUS

Outgoing (742)

TargetRelationTypeStr
DIABETIC RETINOPATHYcausesgene1.00
Diabetesassociated_withdisease1.00
Oxidative Stresstherapeutic_targetpathway1.00
Alstherapeutic_targetdisease1.00
Cancertherapeutic_targetdisease1.00

Incoming (473)

SourceRelationTypeStr
OXIDATIVE STRESStherapeutic_targetgene1.00
INSULIN RESISTANCEactivatesgene0.90
PI3Kactivatesgene0.80
TNFactivatesgene0.80
PI3Ktherapeutic_targetgene0.80

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

HypothesisScoreDiseaseAnalysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMIDAuthorsJournalYearCitations
No papers found