Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GLIAL CELLS: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GLIAL CELLS |
| Summary | Page for Glial Cells |
Knowledge base pages for this entity
graph TD
GLIAL_CELLS["GLIAL CELLS"]
GLIAL_CELLS -->|"component_of"| Neurovascular_Unit["Neurovascular Unit"]
GLIAL_CELLS -->|"causes"| Neuronal_Damage["Neuronal Damage"]
GLIAL_CELLS -->|"upregulates"| Proinflammatory_Cytokines["Proinflammatory Cytokines"]
GLIAL_CELLS -->|"involved_in"| Parkinson_s_Disease["Parkinson's Disease"]
GLIAL_CELLS -->|"involved_in"| Neuroinflammation["Neuroinflammation"]
GLIAL_CELLS -->|"involved_in"| Alzheimer_s_Disease["Alzheimer's Disease"]
GLIAL_CELLS -->|"involved_in"| Synapse_Pathology["Synapse Pathology"]
CYTOKINES["CYTOKINES"] -->|"activates"| GLIAL_CELLS
Irinotecan["Irinotecan"] -->|"targets"| GLIAL_CELLS
STING_Signaling["STING Signaling"] -->|"expressed in"| GLIAL_CELLS
CGAS["CGAS"] -->|"expressed in"| GLIAL_CELLS
cGAS_STING["cGAS-STING"] -->|"expressed in"| GLIAL_CELLS
TDP_43["TDP-43"] -->|"interacts"| GLIAL_CELLS
SNCA["SNCA"] -->|"expressed in"| GLIAL_CELLS
CLU["CLU"] -->|"expressed in"| GLIAL_CELLS| Target | Relation | Type | Str |
|---|---|---|---|
| INFLAMMATORY AND NEUROTOXIC MOLECULES | releases | compound | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Glial Surface Molecules | expressed_in | biomarker | 0.95 |
| LL-37 | activates | protein | 0.95 |
| LL-37 | activates | protein | 0.90 |
| CYTOKINES | activates | protein | 0.90 |
| Irinotecan | targets | drug | 0.85 |
| STING Signaling | expressed_in | pathway | 0.85 |
| Systemic Immune Activation | activates | process | 0.85 |
| PARKINSON'S DISEASE | associated_with | disease | 0.85 |
| CGAS | expressed_in | protein | 0.80 |
| cGAS-STING | expressed_in | pathway | 0.80 |
| STING | expressed_in | protein | 0.80 |
| TARDBP | modulates | protein | 0.80 |
| LL-37 | activates | protein | 0.80 |
| TDP-43 | interacts_with | protein | 0.75 |
| Cgas-Sting Pathway | expressed_in | pathway | 0.75 |
| SNCA | expressed_in | protein | 0.70 |
| CLU | expressed_in | gene | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||