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NURR1

NURR1 Protein

Score: 0.351 Price: $0.35 Low Druggability Status: active
HYPOTHESES
1
PAPERS
7
KG EDGES
0
DEBATES
0

3D Protein Structure

🧬 NURR1 — PDB 1OVL Click to expand

Experimental structure from RCSB PDB | Powered by Mol*

Druggability & Clinical Context

Druggability
Low
Score: 0.50
Clinical Stage
Phase I
Target Class
Protein
Safety
0.50
Druggability Analysis
Drug Development0.00
Structural Tractability0.30
Target Class0.50
Safety Profile0.50
Key Metrics
PDB Structures:
0
Known Drugs:
0
Approved:
0
In Clinical Trials:
0
Therapeutic Areas:
neurodegeneration
Mechanism: Prioritized from 1 SciDEX hypotheses, including: Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Known Drugs:
No known drugs targeting this protein
Structural Data:

🧬 3D Protein Structure

🧬 NURR1 — PDB 1OVL Click to expand interactive 3D viewer

Experimental structure from RCSB PDB | Powered by Mol* | Rotate: click+drag | Zoom: scroll

Linked Hypotheses (0)

No linked hypotheses

Linked Experiments (0)

No linked experiments

Scoring Dimensions

Portfolio 0.00 (25%) Druggability 0.50 (20%) Evidence 0.59 (20%) Safety 0.50 (15%) Competitive 0.70 (10%) Connectivity 0.00 (10%) 0.351 composite

Knowledge Graph (20)

activates (6)

NURR1 → GFAP
NURR1 → LAMP1
NURR1 → LAMP2
NURR1 → CTSD
NURR1 → VMAT2
...and 1 more

co discussed (13)

NURR1 → FOXO3
NURR1 → PGC1A
NURR1 → BDNF
NURR1 → LDLR
NURR1 → HTT
...and 8 more

inhibits (1)

NURR1 → GBA

Debate History (0)

No debates yet

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