gene 1,761 words KG: ent-gene-53dc06f9
Contents

ASCL1 Gene

🧬 Gene Info
Gene SymbolASCL1
Full NameAchaete-Scute Homolog 1
Chromosome12p23.2
Protein TypeTranscription Factor
Functionis a basic helix-loop-helix (bHLH) transcription factor essential for neural development, neurogenesis, and the differentiation of specific neuronal lineages.
Primary Expressionmultiple developmental contexts:
Molecular Weight26.8 kDa
Amino Acids237 aa
UniProt IDP50567
NCBI Gene ID41
Ensembl IDENSG00000139352
OMIM100800
GeneCardsASCL1
Human Protein AtlasASCL1
Canonical E-boxCANNTG (preferred: CAGCTG, CACGTG)
Associated DiseasesCancer, Lung Cancer, Tumor
InteractionsBCL2, Bdnf, BDNF, CANCER, DNA, GBM
KG Connections116 knowledge graph edges
DatabasesGeneCardsHPASTRING

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