| Gene Symbol | NEURON |
| Chromosome | 12p13 |
| Protein Type | Enzyme |
| Function | is a glycolytic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolysis pathway. |
| Primary Expression | neuroendocrine cells) | |
| Molecular Weight | ~45 kDa (each subunit, 433 amino acids) |
| Amino Acids | 433 aa |
| Pathways | NEURODEGENERATION, NEUROINFLAMMATION |
| GeneCards | NEURON |
| Human Protein Atlas | NEURON |
| Gene | ENO2 |
| Isoforms | α (non-neuronal), β (muscle), γ (neuronal) |
| CSF elevations | Elevated in PD patients vs. healthy controls (Santos et al., 2020) |
| Neuronal loss | Reflects ongoing neuronal degeneration |
| Disease progression | Higher levels in moderate to severe AD |
| Associated Diseases | Alzheimer's disease |
| Known Drugs/Compounds | rabies virus glycoprotein peptide, RVG peptide |
| KG Connections | 34 knowledge graph edges |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
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