gene 1,670 words KG: C2
Contents

C2 (Complement Component 2)

🧬 Gene Info
Gene SymbolC2
Full NameComplement Component 2
Chromosome6p21.3
Functionencodes a 732-amino acid zymogen that, upon activation, generates the C3 convertase complex essential for complement cascade amplification.
Molecular Weight83 kDa
Amino Acids732 aa
Exons18
UniProt IDP06610
NCBI Gene ID717
Ensembl IDENSG00000166278
OMIM120490
GeneCardsC2
Human Protein AtlasC2
Associated Diseasesautism spectrum disorder
InteractionsMAVS, PI3KC3, SIRT2
KG Connections17 knowledge graph edges
DatabasesGeneCardsHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

C2 inhibits SIRT2
C2 associated_with TGFB1
C2 associated_with C3
C2 associated_with C5
C2 activates MAVS
C2 expressed_in C6
C2 inhibits Huntington's disease
C2 associated_with autism spectrum disorder
C2 interacts_with PI3KC3
C2 participates_in PI3K-AKT-mTOR signaling

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