gene 2,879 words KG: CD33
Contents

CD33 — Cluster of Differentiation 33

🧬 Gene Info
Gene SymbolCD33
Full NameCluster of Differentiation 33
AliasesSiglec-3
Chromosome19q13.41
FunctionSialic acid binding: Recognizes α2,6-linked sialic acids on glycoproteins
Molecular Weight67 kDa
Amino Acids354 aa
Exons7
Gene TypeProtein coding
PathwaysApoptosis, Autophagy, Blood-Brain Barrier, Dysbiosis, Epigenetic
UniProt IDP07846
NCBI Gene ID945
Ensembl IDENSG00000141548
OMIM159590
GeneCardsCD33
Human Protein AtlasCD33
Associated DiseasesALS, ALZHEIMER, ALZHEIMER'S DISEASE, APOPTOSIS, Aging
Known Drugs/CompoundsStem Cell Therapy
InteractionsOVERVIEW, PSEN1, BCL2, APP, DAP12, APOE
KG Connections708 knowledge graph edges
DatabasesGeneCardsHPASTRING

Knowledge Graph

Knowledge Graph (12 edges)

CD33 mediates TREM2
CD33 mediates TYROBP
CD33 associated_with CR1
CD33 associated_with CTSB
CD33 associated_with CTSH
CD33 associated_with EED
CD33 associated_with GRN
CD33 associated_with INPP5D
CD33 associated_with LILRB2
CD33 associated_with PICALM