Contents

TYROBP Protein (DAP12)

🔬 Protein Info

Gene Symbol	TYROBP
Aliases	DAP12
Chromosome	19q13.12
Protein Type	Adaptor Protein
Function	is a transmembrane signaling adaptor protein that plays critical roles in innate immunity and microglial function in the central nervous system.
Primary Expression	Microglia, Monocytes, NK cells, Osteoclasts
Molecular Weight	12.1 kDa
Amino Acids	113 aa
Pathways	Innate Immunity
UniProt ID	Q9Y241
NCBI Gene ID	7305
Ensembl ID	ENSG00000111653
OMIM	605712
GeneCards	TYROBP
Human Protein Atlas	TYROBP
Associated Diseases	ALS, ALZHEIMER'S DISEASE, Aging, Alzheimer
Known Drugs/Compounds	BERBERINE
Interactions	RANK, OVERVIEW, TREM2, DAP12, APOE, SPI1
SciDEX Hypotheses	TYROBP (DAP12) Conditional Antagonism for Early-St
KG Connections	394 knowledge graph edges
Databases	GeneCards HPA STRING

Knowledge Graph