cell 613 words KG: NEURONS 2026-03-24
kind:cell-typesection:cell-typesstate:published
Contents

Nicotinic Acetylcholine Alpha-7 Receptor Neurons

🧫 Cell Type Info
Cell TypeNicotinic Acetylcholine Alpha-7 Receptor Neurons
Also Known AsNerve cell, Neuronal cell
FunctionsElectrical signal transmission, Synaptic neurotransmitter release, Neural circuit formation, Information processing and storage, Neuroendocrine signaling
Associated DiseasesAlzheimer's disease (neuronal loss), Parkinson's disease (dopaminergic neuron loss), ALS (motor neuron degeneration), Huntington's disease (striatal neuron loss), Epilepsy (hyperexcitability)
Related GenesTNF-α, α-Synuclein
Linked Hypotheses171 hypotheses

Knowledge Graph

Related Hypotheses (10)

Circadian Glymphatic Entrainment via Targeted Orexin Recepto
Score: 0.62
Direct Toxicity Hypothesis: β-Amyloid Directly Impairs Choli
Score: 0.60
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Enhancing Vagal Cholinergic Signaling to Restore Gut-Brain A
Score: 0.51

Related Analyses (14)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
Perivascular spaces and glymphatic clearance failure in AD
neurodegeneration · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived

Related Experiments (3)

HFD-induced cognitive dysfunction and neuroinflammation in m
validation · proposed · Score: 0.90
α7nAChR agonist treatment rescues HFD-induced memory deficit
validation · proposed · Score: 0.85
α7nAChR knockout mice show enhanced HFD sensitivity
validation · proposed · Score: 0.80

Knowledge Graph (12 edges)

NEURONS co_discussed RAGE
NEURONS activates STING
NEURONS causes PARKIN
NEURONS causes PARKINSON
NEURONS causes PARKINSON'S
NEURONS causes PARKINSON'S DISEASE
NEURONS associated_with RAGE
NEURONS activates RAGE
NEURONS co_discussed PARKIN
NEURONS protects_against PARKIN