cell 1,625 words KG: VGLUT2 2026-03-25
kind:cell-typesection:cell-typesstate:published
Contents

Subthalamic Nucleus Glutamatergic Neurons

🧫 Cell Type Info
Cell TypeSubthalamic Nucleus Glutamatergic Neurons
Also Known AsVesicular Glutamate Transporter 2
Key PathwaysEpigenetic, Synaptic Plasticity, Synaptic Vesicle
Associated DiseasesParkinson's disease, Alzheimer's disease, ALS
Related GenesVGLUT1, SLC17A7, KDM6B, SLC17A6, TAU
Linked Hypotheses2 hypotheses

Knowledge Graph

Related Hypotheses (7)

Bacterial Enzyme-Mediated Dopamine Precursor Synthesis
Score: 0.36
Synthetic Biology BBB Endothelial Cell Reprogramming
Score: 0.57
Senescent Cell Mitochondrial DNA Release
Score: 0.54
Layer V excitatory neurons show selectively enhanced vulnera
Score: 0.51
Excitatory Neuron Vulnerability via SLC17A7 Downregulation
Score: 0.44

Related Analyses (10)

Selective vulnerability of entorhinal cortex layer II neuron
neurodegeneration · archived
Blood-brain barrier transport mechanisms for antibody therap
neurodegeneration · archived
Senolytic therapy for age-related neurodegeneration
neurodegeneration · archived
What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived
Mitochondrial transfer between neurons and glia
neurodegeneration · archived

Related Experiments (4)

ER-Golgi Secretory Pathway Dysfunction in PD - Experiment De
clinical · proposed · Score: 0.40
Macroautophagy Dysfunction in PD - Experiment Design
clinical · proposed · Score: 0.40
Sex differences in CB1R-mediated cannabinoid analgesia in ne
validation · proposed · Score: 0.90
Electrophysiological analysis of mPFC-vlPAG synaptic transmi
exploratory · proposed · Score: 0.85

Knowledge Graph (12 edges)

VGLUT2 associated_with VGLUT1
VGLUT2 expressed_in Dentate Gyrus
VGLUT2 activates SLC17A7
VGLUT2 expressed_in KDM6B
VGLUT2 expressed_in VGLUT1
VGLUT2 activates SLC17A6
VGLUT2 activates TAU
VGLUT2 activates Synaptic Vesicle
VGLUT2 associated_with epilepsy
VGLUT2 associated_with neurodegeneration