gene 2,335 words KG: EBF3
Contents

EBF3 — Early B-cell Factor 3

🧬 Gene Info
Gene SymbolEBF3
Full NameEarly B-cell Factor 3
Primary Expressionmature neurons, where it contributes to synaptic plasticity and cognitive function[@coe2019][@ebf2020]
Molecular Weight65 kDa
PathwaysDna Methylation, Epigenetic
Ensembl IDENSG00000108001
GeneCardsEBF3
Human Protein AtlasEBF3
Direct DNA BindingBinds to specific palindromic sequences in target gene promoters and enhancers
Chromatin RemodelingRecruits chromatin-modifying enzymes to open or close chromatin
Transcriptional Activation/RepressionCan both activate and repress target genes depending on context
Protein Complex FormationForms homodimers and heterodimers with other COE proteins
Associated DiseasesAlzheimer's disease, Parkinson's disease
KG Connections30 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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🌐 Cross-references

NCBI GeneUniProtGeneCardsWikipediaHGNCEnsembl

Knowledge Graph (12 edges)

CDK4 regulates EBF3
RB1 associated_with EBF3
EBF3 regulates MYC
EBF3 regulates TP53
EBF3 regulates MDM2
EBF3 regulates GBM
MDM2 regulates EBF3
TP53 regulates EBF3
EBF3 associated_with RB1
MYC regulates EBF3

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