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Home / Wiki / Entity: PRNP (Prion Protein Gene)

entity 1,035 words KG: PRNP 2026-03-22

kind:entity section:entities state:published

Contents

PRNP (Prion Protein Gene)

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63 Heat Shock Protein 70 Disaggregase Amplification
Score: 0.51 Ocular Immune Privilege Extension
Score: 0.47 Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45 Enteric Nervous System Prion-Like Propagation Blockade
Score: 0.44

Serine/Arginine-Rich Protein Kinase Modulation
Score: 0.42 Microbiome-Derived Tryptophan Metabolite Neuroprotection
Score: 0.41

Related Analyses (9)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived What are the mechanisms by which gut microbiome dysbiosis in
neurodegeneration · archived Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed Protein aggregation cross-seeding across neurodegenerative d
neurodegeneration · archived RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · archived

Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · archived Tau propagation mechanisms and therapeutic interception poin
neurodegeneration · failed RNA binding protein dysregulation across ALS FTD and AD
neurodegeneration · completed TDP-43 phase separation therapeutics for ALS-FTD
neurodegeneration · archived

Related Experiments (2)

Pre-Symptomatic Detection and Intervention Timing in Genetic
validation · proposed · Score: 0.40 Prion Strain Diversity and Selective Vulnerability in CJD
clinical · proposed · Score: 0.40

See Also (12)

Packard Center for ALS Research
institution · KG edge: associated_with Alzheimer Indonesia
institution · KG edge: activates PLAU Gene (Urokinase)
gene · KG edge: associated_with MAPT (Microtubule-Associated Protein Tau) Gene
gene · KG edge: associated_with IL1A — Interleukin 1 Alpha
gene · KG edge: associated_with

IL10 — Interleukin 10
gene · KG edge: associated_with IDE Gene - Insulin-Degrading Enzyme
gene · KG edge: associated_with BDNF Gene
gene · KG edge: associated_with ACE Gene
gene · KG edge: associated_with IL6 (Redirect)
redirect · KG edge: associated_with BACE1 (Redirect)
redirect · KG edge: associated_with Amyloid-Related Imaging Abnormalities (ARIA)
entity · KG edge: regulates

Knowledge Graph (12 edges)

PRNP associated_with Creutzfeldt-Jakob

PRNP associated_with IDE

PRNP associated_with TGFB1

PRNP associated_with BACE1

PRNP associated_with HSPG2

PRNP associated_with IL10

PRNP associated_with ACE

PRNP associated_with SORL1

PRNP associated_with BDNF

PRNP associated_with MAPT

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