gene 682 words KG: OLIG2
Contents

OLIG2 Gene

🧬 Gene Info
Gene SymbolOLIG2
PathwaysNotch, Tgf-Β, Pi3K, Apoptosis, Synaptic Plasticity
GeneCardsOLIG2
Human Protein AtlasOLIG2
Motor neuron specificationDuring development, OLIG2 works with NKX2.2 to specify motor neuron fate in the ventral neural tube
OPC specificationDirects neural progenitor cells toward the oligodendrocyte lineage
Proliferation controlRegulates OPC proliferation in response to PDGF and other growth factors
DifferentiationWorks with SOX10 to activate myelin gene expression
Myelin formationEssential for the differentiation of OPCs into mature oligodendrocytes
InteractionsAKT1, ALZHEIMER, ALZHEIMER'S DISEASE, AND, APOPTOSIS, ASCL1
SciDEX HypothesesMyelin Interface Restoration Therapy
KG Connections111 knowledge graph edges
DatabasesGeneCardsUniProtNCBI GeneHPASTRING

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