gene 682 words KG: OLIG2 2026-03-15
kind:genesection:genesstate:published
Contents

OLIG2 Gene

🧬 Gene Info
Gene SymbolOLIG2
Full NameOligodendrocyte Transcription Factor 2
Chromosome21q22.11
PathwaysNotch, Tgf-Β, Pi3K, Apoptosis, Synaptic Plasticity
NCBI Gene ID10215
Ensembl IDENSG00000132588
GeneCardsOLIG2
Human Protein AtlasOLIG2
UniProt ID Q9Y6X7| OMIM ID 607343
InteractionsTNF, SOX10, SOX9, STAT1, SHH, TCF7L2
KG Connections112 knowledge graph edges
DatabasesGeneCardsUniProtHPASTRING

Knowledge Graph

Related Hypotheses (7)

CYP46A1 Overexpression Gene Therapy
Score: 0.63
GFAP-Positive Reactive Astrocyte Subtype Delineation
Score: 0.52
Astrocytic Lipoxin A4 Pathway Restoration via ALOX15 Gene Th
Score: 0.45
Oligodendrocyte Protectin D1 Mimetic for Myelin Resolution
Score: 0.45
Programmable Neuronal Circuit Repair via Epigenetic CRISPR
Score: 0.42

Related Analyses (6)

Neuroinflammation resolution mechanisms and pro-resolving me
neurodegeneration · archived
Lipid raft composition changes in synaptic neurodegeneration
neurodegeneration · completed
Epigenetic reprogramming in aging neurons
neurodegeneration · archived
Circuit-level neural dynamics in neurodegeneration
neuroscience · archived
Gene expression changes in aging mouse brain predicting neur
neurodegeneration · archived

See Also (15)

CREB-independent Neuronal Survival Pathways
mechanism · KG edge: inhibits
Apoptosis Pathway in Neurodegeneration
mechanism · KG edge: inhibits
Packard Center for ALS Research
institution · KG edge: inhibits
Alzheimer Indonesia
institution · KG edge: inhibits
NESTIN: Intermediate Filament Protein in Neural Stem Ce
gene · KG edge: associated_with

Knowledge Graph (12 edges)

OLIG2 inhibits TNF
OLIG2 expressed_in neurodegeneration
OLIG2 activates SOX10
OLIG2 participates_in insulin signaling
OLIG2 interacts_with SOX9
OLIG2 causes MOG
OLIG2 targets MOG
OLIG2 co_discussed PARP1
OLIG2 co_discussed oligodendrocyte
OLIG2 co_discussed myelin